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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameAzide-PEG4-Tos
SynonymsN3-PEG5-Tos;AZIDE-PEG5-TOS;Azido-PEG5-OTs;Azido-PEG5-Tos;Azide-PEG4-Tos;Azide-PEG5-Tos;N3-PEG5-TOS AZIDE-PEG5-TOS;14-azido-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate
CAS236754-49-7
EINECS
Chemical FormulaC17H27N3O7S
Molecular Weight417.48
inchi
Package50 mg;100 mg;250 mg;500 mg;1 g
PriceEmail to quote
DescriptionsAzide-PEG5-Tos

Azide-PEG5-Tos

MedChemExpress (MCE)

HY-140352

236754-49-7

98.49%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Azide-PEG5-Tos

Azide-PEG5-Tos

MedChemExpress (MCE)

HY-140352

236754-49-7

98.49%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/azide-peg5-tos.html
Last Update2025-05-21 16:50:25
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