Bis-propargyl-PEG1 MedChemExpress (MCE)

Product Name	Ethylene Glycol 1,2-Bis(2-propynyl) Ether
Synonyms	Bis-propargyl-PEG1;Alkyne-PEG2-Alkyne;PROPARGYL-PEG2-PROPARGYL;1,2-Bis(2-propynyloxy)ethane;Ethylene Glycol 1,2-Bis(2-propynyl) Ether;1-Propyne, 3,3'-[1,2-ethanediylbis(oxy)]bis-
CAS	40842-04-4
EINECS	808-107-1
Chemical Formula	C8H10O2
Molecular Weight	138.16
inchi
Package	100 mg;500 mg;1 g;5 g;10 g
Price	Email to quote
Descriptions	Bis-propargyl-PEG1 Bis-propargyl-PEG1 MedChemExpress (MCE) HY-140038 40842-04-4 98.0% 4°C, stored under nitrogen In solvent : -80°C, 6 months Descriptions Bis-propargyl-PEG1 Bis-propargyl-PEG1 MedChemExpress (MCE) HY-140038 40842-04-4 98.0% 4°C, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (stored under nitrogen) Room temperature in continental US may vary elsewhere. Bis-propargyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bis-propargyl-PEG1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Supplier Website	https://www.medchemexpress.com/bis-propargyl-peg1.html
Last Update	2025-05-21 16:50:25

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