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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameTert-butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oate
SynonymsTos-PEG4-CH2-Boc
Tos-PEG4-CH2COOtBu
Tos-PEG5-CH2CO2tBu
Tos-PEG4-t-butyl acetate
Tos-PEG5-CH2CO2t-butyl ester
Tert-butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oate
tert-butyl 2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetate

Synonyms

Tos-PEG4-CH2-Boc
Tos-PEG4-CH2COOtBu
Tos-PEG5-CH2CO2tBu
Tos-PEG4-t-butyl acetate
Tos-PEG5-CH2CO2t-butyl ester
Tert-butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oate
tert-butyl 2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetate
2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-acetic acid tert-butyl ester
3,6,9,12-Tetraoxatetradecanoic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
CAS169751-73-9
EINECS
Chemical FormulaC21H34O9S
Molecular Weight462.55
inchi
Package100 mg;250 mg
PriceEmail to quote
DescriptionsTos-PEG4-CH2-Boc

Tos-PEG4-CH2-Boc

MedChemExpress (MCE)

HY-42620

169751-73-9

95.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Tos-PEG4-CH2-Boc

Tos-PEG4-CH2-Boc

MedChemExpress (MCE)

HY-42620

169751-73-9

95.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs Alkyl/ether

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[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16
50(4):34.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/tos-peg4-ch2-boc.html
Last Update2025-04-01 14:45:47
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