Norbiotinamine MedChemExpress (MCE)

Product Name	(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
Synonyms	Norbiotinamine;(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one;1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-(4-aminobutyl)tetrahydro-, (3aS,4S,6aR)-
CAS	173401-47-3
EINECS
Chemical Formula	C9H17N3OS
Molecular Weight	215.32
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Norbiotinamine Norbiotinamine MedChemExpress (MCE) HY-135717 173401-47-3 99.80% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Norbiotinamine Norbiotinamine MedChemExpress (MCE) HY-135717 173401-47-3 99.80% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction. In order to couple biotin to amino acids, reaction has to be with an amino group. An example is biocytin (biotin lysine). However, Norbiotinamine could be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction. As an example, Norbiotinamine is coupled with the NHS ester of N-Boc-glutamic acid γ-benzyl ester. The resulting norbiotinylamide of γglutamic acid (VII), obtained after deprotection, is similar to biocytin, but it has a shorter aliphatic chain and an inverted amide bond[1]. \| \| \| \| \| \| \| \| \| \| [1]. Szalecki W.Synthesis of Norbiotinamine and its derivatives. Bioconjug Chem. 1996 Mar-Apr 7(2):271-3. [Content Brief] [2]. Zhou GC, et al. Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells.Eur J Med Chem. 2013 70:631-9. [Content Brief]
Supplier Website	https://www.medchemexpress.com/norbiotinamine.html
Last Update	2025-05-21 16:50:25

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