Afoxolaner MedChemExpress (MCE)

Product Name	AFOXOLANER
Synonyms	AFOXOLANER Afoxolaner afoxolaner-007 Afoxolaner fandachem 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide Synonyms AFOXOLANER Afoxolaner afoxolaner-007 Afoxolaner fandachem 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-
CAS	1093861-60-9
EINECS
Chemical Formula	C26H17ClF9N3O3
Molecular Weight	625.87
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Afoxolaner Afoxolaner MedChemExpress (MCE) HY-16974 1093861-60-9 99.95% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Afoxolaner Afoxolaner MedChemExpress (MCE) HY-16974 1093861-60-9 99.95% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod. A single oral treatment with a dose approaching the minimum effective dose of Afoxolaner (2.5mg/kg) eliminated the pre-existing infestations of I. scapularis ticks and controlled weekly re-infestations, with efficacy between 98% and 100% recorded until Day 23 and 94% at Day 30[1]. Mite \| \| \| \| \| \| \| \| \| \| [1]. Mitchell EB, et al. Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.Vet Parasitol. 2014 Apr 2 201(3-4):223-5. [Content Brief] [2]. Beugnet F, et al. Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs.Parasite. 2014 21:42. [Content Brief]
Supplier Website	https://www.medchemexpress.com/afoxolaner.html
Last Update	2025-05-21 16:50:25

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