TBPB MedChemExpress (MCE)

Product Name	TBPB
Synonyms	TBPB 1-(1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one 1,3-Dihydro-1-[1'-[(2-methylphenyl)methyl][1,4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one 2H-BenziMidazol-2-one, 1,3-dihydro-1-[1'-[(2-Methylphenyl)Methyl][1,4'-bipiperidin]-4-yl]-
CAS	634616-95-8
EINECS
Chemical Formula	C25H32N4O
Molecular Weight	404.55
inchi
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	TBPB TBPB MedChemExpress (MCE) HY-14562 634616-95-8 99.74% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions TBPB TBPB MedChemExpress (MCE) HY-14562 634616-95-8 99.74% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. TBPB is an allosteric M1 mAChR agonist(EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. mAChR1 \| \| \| \| \| \| \| \| \| \| [1]. Jones CK, et al. Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. J Neurosci. 2008 Oct 8 28(41):10422-33. [Content Brief] [2]. Miller NR, et al. Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen. Bioorg Med Chem Lett. 2008 Oct 15 18(20):5443-7. [Content Brief]
Supplier Website	https://www.medchemexpress.com/TBPB.html
Last Update	2025-05-21 16:50:25

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