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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameAlcaftadine
SynonymsR 89674
Lastacaft
ALCAFTADINE
Alcaftadine
UNII-7Z8O94ECSX
Alcaftadine (R89674)
6,11-Dihydro-11-(1-Methyl-4-piperidinylidene)-5H-iMidazo[2,1-b][3]benzazepine-3-carboxaldehyde

Synonyms

R 89674
Lastacaft
ALCAFTADINE
Alcaftadine
UNII-7Z8O94ECSX
Alcaftadine (R89674)
6,11-Dihydro-11-(1-Methyl-4-piperidinylidene)-5H-iMidazo[2,1-b][3]benzazepine-3-carboxaldehyde
5H-IMidazo[2,1-b][3]benzazepine-3-carboxaldehyde,6,11-dihydro-11-(1-Methyl-4-piperidinylidene)-
12-(1-Methylpiperidin-4-ylidene)-4,6,7,12-tetrahydrobenzo[d]pyriMido[1,2-a]azepine-3-carbaldehyde
5H-Imidazo(2,1-b)(3)benzazepine-3-carboxaldehyde, 6,11-dihydro-11-(1-methyl-4- piperidinylidene)-
CAS147084-10-4
EINECS1308068-626-2
Chemical FormulaC19H21N3O
Molecular Weight307.39
inchi
Package10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsAlcaftadine

Alcaftadine

MedChemExpress (MCE)

HY-17039

147084-10-4

R89674

98.37%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US

Descriptions

Alcaftadine

Alcaftadine

MedChemExpress (MCE)

HY-17039

147084-10-4

R89674

98.37%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US
may vary elsewhere.

Alcaftadine (R89674) is a histamine H1 receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects.

H1 Receptor H2 Receptor

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[1]. Namdar, R. and C. Valdez, Alcaftadine: a topical antihistamine for use in allergic conjunctivitis. Drugs Today (Barc), 2011. 47(12): p. 883-90. [Content Brief]

[2]. Mahvan, T.D., W.A. Buckley, and J.R. Hornecker, Alcaftadine for the prevention of itching associated with allergic conjunctivitis. Ann Pharmacother, 2012. 46(7-8): p. 1025-32. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/Alcaftadine.html
Last Update2025-05-21 16:50:25
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