Trospium MedChemExpress (MCE)

Product Name	Trospium chloride
Synonyms	keptan asxvii relaspium oride,benzilate Trosipum Chloride Trospium chloride azoniaspirocompoundxvii Synonyms keptan asxvii relaspium oride,benzilate Trosipum Chloride Trospium chloride azoniaspirocompoundxvii Trospium Chloride intermediate 8-alpha-benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decanechloride azoniaspiro(3-alpha-benziloyloxy-nortropan-8,1'-pyrrolidine)-chloride azoniaspiro(3-alpha-benziloyloxy-nortropan-8,1'-pyrrolidine)-chloride 5-alpha-h-nortropane-8,1'-pyrrolidinium),3-alpha-hydroxy-spiro(1-alpha-chl -5-alpha-h-nortropane-8,1'-pyrrolidinium),3-alpha-hydroxy-spiro(1-alpha-chl spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl 2-hydroxy-2,2-diphenyl-acetate chloride (1a,3,5a)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride 2-hydroxy-2,2-diphenylacetic acid [(1S,5R)-3-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]yl] ester chloride
CAS	10405-02-4
EINECS	233-875-4
Chemical Formula	C25H30ClNO3
Molecular Weight	427.96
inchi	InChI=1/C25H30NO3/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26/h1-6,9-12,21-23,28H,7-8,13-18H2/q+1/t21-,22+,23+
Package	10 mM * 1 mL;100 mg
Price	Email to quote
Descriptions	Trospium chloride Trospium chloride MedChemExpress (MCE) HY-B0461 10405-02-4 99.88% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Trospium chloride Trospium chloride MedChemExpress (MCE) HY-B0461 10405-02-4 99.88% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors. Trospium chloride (1 nM-100 μM) inhibits Carbachol (HY-B1208)-induced contraction of human detrusor smooth muscle with an EC50 of 3 nM[2]. Trospium chloride (0.1-0.5 mg/kg, iv, single dose) inhibits the gastric and intestinal motility in dog models[1]. mAChR1 mAChR2 mAChR3 \| \| \| \| \| \| \| \| \| \| [1]. David RP Guay. Trospium chloride: an update on a quaternary anticholinergic for treatment of urge urinary incontinence. Ther Clin Risk Manag. 2005 Jun 1(2): 157–167. [Content Brief] [2]. Eric S Rovner, et al. Trospium chloride in the management of overactive bladder. Drugs. 2004 64(21):2433-46. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Trospium-chloride.html
Last Update	2025-05-21 16:50:25

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