Lck inhibitor 2 MedChemExpress (MCE)

Product Name	BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-
Synonyms	Lck inhibitor 2 3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]- 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide 3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide Synonyms Lck inhibitor 2 3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]- 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide 3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-
CAS	944795-06-6
EINECS
Chemical Formula	C18H17N5O2
Molecular Weight	335.36
inchi
Package	10 mM * 1 mL;5 mg;10 mg
Price	Email to quote
Descriptions	Lck inhibitor 2 Lck inhibitor 2 MedChemExpress (MCE) HY-10644 944795-06-6 99.73% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Lck inhibitor 2 Lck inhibitor 2 MedChemExpress (MCE) HY-10644 944795-06-6 99.73% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Lck inhibitor 2 is a multi-target tyrosine kinase inhibitor with IC50s of 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively. \| \| \| \| \| \| \| \| \| \| [1]. Bamborough, et al. Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery. Journal of Medicinal Chemistry (2008), 51(24), 7898-7914. [Content Brief] [2]. Bamborough, Paul, et al. N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics. Bioorganic & Medicinal Chemistry Letters (2007), 17(15), 4363-4368. [Content Brief] [3]. Awale, Mahendra, et al. Molecular docking guided 3D-QSAR CoMFA analysis of N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of leukocyte-specific protein tyrosine kinase. Journal of Molecular Modeling (2008), 14(10), 937-947. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Lck-inhibitor-2.html
Last Update	2025-05-21 16:50:25

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