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Supplier Contact

Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
QQ
Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
Wechat
Product NameEntrectinib
SynonymsRXDX-101
Entrectinib
entrecitinib
NVP-LGK974, WNT974
Entrectinib(NMS-E628)
N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzamide

Synonyms

RXDX-101
Entrectinib
entrecitinib
NVP-LGK974, WNT974
Entrectinib(NMS-E628)
N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzamide
N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)amino]benzamide
CAS1108743-60-7
EINECS
Chemical FormulaC31H34F2N6O2
Molecular Weight560.6375
inchi
Package5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
DescriptionsEntrectinib (Standard)

Entrectinib (Standard)

MedChemExpress (MCE)

HY-12678R

1108743-60-7

98%

Please store the product under the recommended conditions in the Certificate of Analysis.

Entrectinib (Standard) is the analytical standard of Entrectinib. This product is intended for research and analytical applications. Entrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice.

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Supplier Websitehttps://www.medchemexpress.com/entrectinib-standard.html
Last Update2025-05-21 16:50:25
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