BSH MedChemExpress (MCE)

Product Name	Dodecaborate(2-),1,2,3,4,5,6,7,8,9,10,11-undecahydro-12-mercapto-, sodium (1:2)
Synonyms	Dodecaborate(2-),1,2,3,4,5,6,7,8,9,10,11-undecahydro-12-mercapto-, sodium (1:2);Sodium mercaptododecaborate, N-BSH
CAS	144885-51-8
EINECS
Chemical Formula	B12HNaS+
Molecular Weight	185.78
inchi
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Borocaptate sodium Borocaptate sodium MedChemExpress (MCE) HY-142041 144885-51-8 BSH 95.0% -20°C, stored under nitrogen, away from moisture In solvent : -80°C, 6 months Descriptions Borocaptate sodium Borocaptate sodium MedChemExpress (MCE) HY-142041 144885-51-8 BSH 95.0% -20°C, stored under nitrogen, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (stored under nitrogen, away from moisture) Room temperature in continental US may vary elsewhere. Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity. Borocaptate sodium (60 μg 10B/mL, 24 hours) combined with BSO (HY-106376) enhances boron uptake and inhibits cell viability in mouse squamous carcinoma cells, rat glioma cells, and hamster lung cells, with boron uptake increasing as cell viability decreases[3]. Borocaptate sodium (55 mg/kg, i.v., single dose) selectively targets intracranial tumors in dogs and inhibits their growth[2]. \| \| \| \| \| \| \| \| \| \| [1]. Bendel P, et al. Optimal detection of the neutron capture therapy agent borocaptate sodium (BSH): A comparison between and NMR[J]. Medical Physics, 2001, 28(2): 178-183. [Content Brief] [2]. Kraft SL, et al. Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. Proc Natl Acad Sci U S A. 1992 Dec 15 89(24):11973-7. [Content Brief] [3]. Yoshida F, et al. Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. Cancer Lett. 2004 Nov 8 215(1):61-7. [Content Brief] [4]. Kokai-Kun J F, et al. Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model[J]. Journal of antimicrobial chemotherapy, 2007, 60(5): 1051-1059. [Content Brief]
Supplier Website	https://www.medchemexpress.com/borocaptate-sodium.html
Last Update	2025-05-21 16:50:25

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