AHR antagonist 7 MedChemExpress (MCE)

Product Name	CAY10464
Synonyms	CAY10464;CAY10464 Exclusive;1,3-dichloro-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene;1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene
CAS	688348-37-0
EINECS
Chemical Formula	C15H12Cl2O
Molecular Weight	279.16
inchi
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	CAY10464 CAY10464 MedChemExpress (MCE) HY-112628 688348-37-0 AHR antagonist 7 99.77% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions CAY10464 CAY10464 MedChemExpress (MCE) HY-112628 688348-37-0 AHR antagonist 7 99.77% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. CAY10464 (AHR antagonist 7 compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a Ki of 1.4 nM. In HepG2 cells, CAY10464 (100 nM) inhibits CYP1A1 mRNA expression, and reverses the suppressive effect of Benzo[a]pyrene on apolipoprotein A-I (apo A-I) gene expression[2]. \| \| \| \| \| \| \| \| \| \| [1]. Philippe de Medina, et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem. 2005 Jan 13 48(1):287-91. [Content Brief] [2]. Emad Naem,et al. Inhibition of apolipoprotein A-I gene by the aryl hydrocarbon receptor: a potential mechanism for smoking-associated hypoalphalipoproteinemia. Life Sci. 2012 Jul 26 91(1-2):64-9. [Content Brief]
Supplier Website	https://www.medchemexpress.com/cay10464.html
Last Update	2025-05-21 16:50:25

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