IMMU-132 (solution) MedChemExpress (MCE)

Product Name	Satralizumab Linker
Synonyms	Satralizumab Linker;Sacituzumab Govitecan
CAS	1491917-83-9
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg
Price	Email to quote
Descriptions	Sacituzumab govitecan (solution) Sacituzumab govitecan (solution) MedChemExpress (MCE) HY-132254A 1491917-83-9 IMMU-132 (solution) 96.61% -80°C, protect from light Shipping with dry ice. Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity. Sacituzumab govitecan (10 µM Descriptions Sacituzumab govitecan (solution) Sacituzumab govitecan (solution) MedChemExpress (MCE) HY-132254A 1491917-83-9 IMMU-132 (solution) 96.61% -80°C, protect from light Shipping with dry ice. Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity. Sacituzumab govitecan (10 µM 48 h) upregulates the early pro-apoptotic signaling markers (cleaved caspase3/7, cleaved PARP, p53 and p21), causes PARP cleavage and apoptosis[3]. Sacituzumab govitecan (IMMU-132) (17.5 mg/kg twice weekly for 4 weeks) produces significant antitumor effects in mice bearing human gastric cancer xenografts[1]. \| \| \| \| \| \| \| \| \| \| [1]. Cardillo TM, et al. Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers. Bioconjug Chem. 2015 May 20 26(5):919-31. [Content Brief] [2]. Goldenberg DM, Cardillo TM, Govindan SV, Rossi EA, Sharkey RM. Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC) [published correction appears in Oncotarget. 2020 Mar 10 11(10):942]. Oncotarget. 2015 6(26):22496-22512. [Content Brief] [3]. Cardillo TM, et al., Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers. Bioconjug Chem. 2015 May 20 26(5):919-31. [Content Brief]
Supplier Website	https://www.medchemexpress.com/sacituzumab-govitecan-solution.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-05-21 16:50:25

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-05-21 16:50:25

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-05-21 16:50:25

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-05-21 16:50:25

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-05-21 16:50:25

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-05-21 16:50:25

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-05-21 16:50:25

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact