ChemBK
  • Home
  • Product Category
  • CHN
  1. Home
  2. CAS 727664-79-1
  3. Supplier List
  4. MedChemExpress (MCE)
  5. Signaling Pathways
  6. Thr101

Request for quotation








Supplier Contact

Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
QQ
Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
Wechat
Product Name6-Fluoro-2-(2-methylphenyl)-1,2-benzisothiazol-3(2H)-one
Synonyms6-Fluoro-2-(2-methylphenyl)-1,2-benzisothiazol-3(2H)-one
CAS727664-79-1
EINECS
Chemical FormulaC14H10FNOS
Molecular Weight259.3
inchi
Package10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
DescriptionsThr101

Thr101

MedChemExpress (MCE)

HY-124890

727664-79-1

99.36%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Thr101

Thr101

MedChemExpress (MCE)

HY-124890

727664-79-1

99.36%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Thr101 is an inhibitor (IC50=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia).

ic50: 2.9 μM (Phosphomannose isomerase, PMI)[1] Molecular Weight 259.30

| | | |

| | | | | |



[1]. Dahl R, et al. Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem. 2011 May 26
54(10):3661-8. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/thr101.html
Last Update2025-05-21 16:50:25
MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-05-21 16:50:25

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-05-21 16:50:25

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-05-21 16:50:25

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-05-21 16:50:25

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-05-21 16:50:25

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-05-21 16:50:25

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-05-21 16:50:25

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-05-21 16:50:25
  • Home
  • Product Category

© 2015 ChemBK.com All Rights Reserved | Build: 20150530002