Name | vidarabine |
Synonyms | vidarabine 2'-ARAADENOSINE ARABINOSYL-ADENINE 9-BETA-D-ARABINOSYLADENINE ADENINE-BETA-D-ARABINOFURANOSIDE 9-BETA-D-ARABINOFURANOSYLADENINE ADENINE-9-BETA-D-ARABINOFURANOSIDE 9-.beta.-D-Arabinofuranosyladenine Adenine, 9-.beta.-D-arabinofuranosyl- 9-β-D-arabinopyranosyl-9H-purin-6-amine 6-AMINO-9-BETA-D-ARABINOFURANOSYLPURINE 6-Amino-9-.beta.-D-arabinofuranosylpurine 9-(beta-D-Arabinofuranosyl)-9H-purin-6-amine 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl- 9-.beta.-D-Arabinofuranosyl-9H-purin-6-amine ADENINE-9-BETA-D-ARABINOFURANOSIDE (VIDARABINE) 9H-purin-6-amine, 9-beta-D-glycero-pentofuranosyl- 9-(beta-D-glycero-Pentofuranosyl)-9H-purin-6-amine |
CAS | 5536-17-4 |
EINECS | 226-893-9 |
InChI | InChI=1/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(16)1-19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1 |
InChIKey | OIRDTQYFTABQOQ-UHTZMRCNSA-N |
Molecular Formula | C10H13N5O4 |
Molar Mass | 267.25 |
Density | 1.3382 (rough estimate) |
Melting Point | 260-265°C (dec.) |
Boling Point | 410.43°C (rough estimate) |
Specific Rotation(α) | D27 -5° (c = 0.25) |
Flash Point | 340.6°C |
Water Solubility | Soluble in DMF (10 mg/ml), 0.5 M HCl (50 mg/ml), DMSO (53 mg/ml at 25°C), ethanol (<1 mg/ml at 25°C), and water (3 mg/ml at 25°C). |
Solubility | Slightly soluble in water (0.45 mg/ml), methanol, almost insoluble in ether. |
Vapor Presure | 3.14E-17mmHg at 25°C |
Appearance | White needle crystal or crystalline powder |
Color | White to Off-white |
Merck | 13,10039 |
BRN | 624881 |
pKa | pKa 3.55(H2Ot=20I=0.1 (KCl)) (Uncertain);11.4 (Uncertain) |
Storage Condition | -20°C |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.7610 (estimate) |
MDL | MFCD00065471 |
Physical and Chemical Properties | This product is white needle-like crystal or crystalline powder. Odorless; Tasteless; Slightly soluble in water (0.45 mg/ml), methanol, almost insoluble in ether. mp259-261. The solubility of this product is 100 mg/ml. |
Risk Codes | R63 - Possible risk of harm to the unborn child R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | 2811 |
WGK Germany | 3 |
RTECS | AU6200000 |
FLUKA BRAND F CODES | 10-23 |
TSCA | Yes |
HS Code | 29349990 |
Hazard Class | 6.1(a) |
Packing Group | II |
Toxicity | LD50 in mice (mg/kg): 4677 i.p.; >7950 orally (Kurtz) |