tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate
4-Benzyloxycarbonylamino-N-Boc-piperdine
CAS: 220394-97-8
Molecular Formula: C18H26N2O4
tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate - Names and Identifiers
| Name | 4-Benzyloxycarbonylamino-N-Boc-piperdine |
| Synonyms | 1-BOC-4-CBZ-AMINO-PIPERIDINE 4-Benzyloxycarbonylamino-N-Boc-piperdine 4-BENZYLOXYCARBONYLAMINO-N-BOC-PIPERIDINE Benzyl 1-(tert-butoxycarbonyl)piperidin-4-ylcarbamate tert-butyl 4-(phenylmethoxycarbonylamino)piperidine-1-carboxylate tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate tert-butyl 4-{[(benzyloxy)carbonyl]amino}piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester |
| CAS | 220394-97-8 |
| InChI | InChI=1/C18H26N2O4/c1-18(2,3)24-17(22)20-11-9-15(10-12-20)19-16(21)23-13-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,19,21) |
tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C18H26N2O4 |
| Molar Mass | 334.41 |
| Density | 1.15±0.1 g/cm3(Predicted) |
| Melting Point | 88 °C |
| Boling Point | 471.6±44.0 °C(Predicted) |
| Flash Point | 239°C |
| Vapor Presure | 4.6E-09mmHg at 25°C |
| pKa | 12.10±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.545 |
tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29333990 |
tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate - Introduction
It is also known as an organic compound. It is a white crystal, with the nature of insoluble in water, but soluble in organic solvents.
In chemical synthesis, it is widely used as a reagent for protecting amino groups. By protecting the amino group, it can be protected from unwanted chemical changes during the reaction. Such compounds are commonly used in Amination Reactions in organic synthesis and in peptide synthesis.
The method of preparation is to react aminopiperidine with Boc-Cl(N-Boc propionyl chloride) and Cbz-Cl (benzoyl chloride) to obtain the desired compound.
Regarding safety information, is a chemical that must be used and operated correctly. It has an irritating effect on the eyes and skin, so appropriate personal protective equipment should be worn during operation. In addition, avoid contact with harmful substances such as strong oxidants and acids during storage and handling to prevent dangerous reactions. When using and handling, refer to the relevant safety data sheets and operating instructions.
In chemical synthesis, it is widely used as a reagent for protecting amino groups. By protecting the amino group, it can be protected from unwanted chemical changes during the reaction. Such compounds are commonly used in Amination Reactions in organic synthesis and in peptide synthesis.
The method of preparation is to react aminopiperidine with Boc-Cl(N-Boc propionyl chloride) and Cbz-Cl (benzoyl chloride) to obtain the desired compound.
Regarding safety information, is a chemical that must be used and operated correctly. It has an irritating effect on the eyes and skin, so appropriate personal protective equipment should be worn during operation. In addition, avoid contact with harmful substances such as strong oxidants and acids during storage and handling to prevent dangerous reactions. When using and handling, refer to the relevant safety data sheets and operating instructions.
Last Update：2024-04-09 20:52:54
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View History
tert-butyl 4-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate
1H,1H,7H-Dodecafluoro-1-heptanol
1-(Benzo[D][1,3]dioxol-5-YL)-2,2,2-trifluoroethanol
[1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate salt
(R)-1-(5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-yl)propan-2-amine
677329-38-3
3-isoquinolin-5-yl-2-tert-butyl-1-(1,3-thiazol-2-yl)guanidine
Lathyrol 34420-19-4
methyl 2-(6-oxo-2-sulfanyl-1,6-dihydropyrimidin-4-yl)acetate
4-Chloro-5-methylresorcinol
1H,1H,7H-Dodecafluoro-1-heptanol
1-(Benzo[D][1,3]dioxol-5-YL)-2,2,2-trifluoroethanol
[1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate salt
(R)-1-(5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-yl)propan-2-amine
677329-38-3
3-isoquinolin-5-yl-2-tert-butyl-1-(1,3-thiazol-2-yl)guanidine
Lathyrol 34420-19-4
methyl 2-(6-oxo-2-sulfanyl-1,6-dihydropyrimidin-4-yl)acetate
4-Chloro-5-methylresorcinol