tert-butyl (1,3-thiazol-4-yl)carbamate
tert-Butyl thiazol-4-ylcarbamate
CAS: 1235406-42-4
Molecular Formula: C8H12N2O2S
tert-butyl (1,3-thiazol-4-yl)carbamate - Names and Identifiers
tert-butyl (1,3-thiazol-4-yl)carbamate - Physico-chemical Properties
| Molecular Formula | C8H12N2O2S |
| Molar Mass | 200.26 |
| Density | 1.242±0.06 g/cm3(Predicted) |
| Melting Point | 153-155 °C |
| Boling Point | 254.9±13.0 °C(Predicted) |
| pKa | 12.39±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD18800853 |
tert-butyl (1,3-thiazol-4-yl)carbamate - Reference Information
| Use | N-BOC-4-aminothiazole is an organic intermediate, which can be made of thiazol-4-formic acid As a raw material, it is prepared by Curtis rearrangement reaction. |
| preparation | compound thiazole -4-formic acid (15g,116mmol) is dissolved with tert-butanol (750ml), DPPA(47.95g,174mmol) and triethylamine (37.5ml,232mmol) are added, reflux reaction is added at 110 ℃ overnight, and the solvent is dried after the reaction is finished, stir with ethyl acetate (400ml), wash with 5% citric acid solution (200ml), wash with water (200ml), wash with saturated sodium bicarbonate solution (200ml), wash with saturated salt water (200ml), dry with anhydrous sodium sulfate, spin-dry solvent silica gel column chromatography purification (PE/EA = 30:1 → 15:1) to obtain compound N-BOC-4-aminothiazole, white solid 16.2g, yield 69.8%. |
Last Update：2024-04-09 21:04:16
Supplier List
Spot supply
Product Name: tert-butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotationCAS: 1235406-42-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: tert-Butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotationCAS: 1235406-42-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: tert-Butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotation
CAS: 1235406-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1235406-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: tert-butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotationCAS: 1235406-42-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: tert-Butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotationCAS: 1235406-42-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: tert-Butyl thiazol-4-ylcarbamate Visit Supplier Webpage Request for quotation
CAS: 1235406-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1235406-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
tert-butyl (1,3-thiazol-4-yl)carbamate
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
5-Chloroimidazo[1,2-A]Pyridine-3-Carbaldehyde
4H-Thieno[2',3':4,5]pyrimido[2,1-b]benzoxazol-4-one, 2-phenyl-
331235-76-8
3-HYDROXY-N-METHYLPIPERIDINE
(1R)-1-Methyl-4α-[(S)-1,2,2-trimethylcyclopentane-1β-yl]-2-cyclohexene-1β-ol
2,5-dichloro-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
2-{4-[(3,4-dichlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
1,4-Benzodioxin-6-carboxamide, N-[3-(5-chloro-2-benzoxazolyl)phenyl]-2,3-dihydro-
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
5-Chloroimidazo[1,2-A]Pyridine-3-Carbaldehyde
4H-Thieno[2',3':4,5]pyrimido[2,1-b]benzoxazol-4-one, 2-phenyl-
331235-76-8
3-HYDROXY-N-METHYLPIPERIDINE
(1R)-1-Methyl-4α-[(S)-1,2,2-trimethylcyclopentane-1β-yl]-2-cyclohexene-1β-ol
2,5-dichloro-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
2-{4-[(3,4-dichlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
1,4-Benzodioxin-6-carboxamide, N-[3-(5-chloro-2-benzoxazolyl)phenyl]-2,3-dihydro-