tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) - Names and Identifiers
Name | tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
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Synonyms | 1-BOC-6-CYANOINDOLE-3-BORONIC ACID, PINACOL ESTER 1-BOC-6-cyanoindole-3-boronic acid, pinacol ester tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) tert‐butyl 6‐cyano‐3‐(tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)‐1H‐indole‐1‐carboxylate tert-butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 1H-Indole-1-carboxylic acid, 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester
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CAS | 1218790-23-8
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tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) - Physico-chemical Properties
Molecular Formula | C20H25BN2O4
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Molar Mass | 368.2345 |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Sensitive | IRRITANT |
MDL | MFCD15143605 |
tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) - Introduction
tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to slightly yellow solid
-Molecular formula: C20H27BN2O4
-Molecular weight: 370.26g/mol
-melting point: 85-87 ℃
-Boiling point: 482.6 ℃
-Soluble: Slightly soluble in ether and dichloromethane, almost insoluble in water
Use:
- tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate is often used as an intermediate in organic synthesis.
-It can be used to prepare compounds with pharmaceutical activity, such as anti-cancer drugs.
-At the same time, it can also be used as a fluorescent probe, dye and labeling reagent.
Preparation Method:
tert-Butyl The preparation method of 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate is complicated and requires organic synthesis technology. A common synthetic method is by reacting indole -1-carboxylic acid and boronic acid dimethyl ester successively with the corresponding reagents under suitable conditions and heating in an appropriate solvent to obtain the target product.
Safety Information:
The specific safety evaluation of tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate may not be complete. In general, however, normal laboratory safety practices should be followed for handling the compound. Avoid contact with skin and eyes, and make sure to operate in a well-ventilated place. If necessary, use personal protective equipment, such as laboratory gloves, goggles, and laboratory coats. For more specific safety information and hazard assessments, consult the Chemical Safety Data Sheet (MSDS) or the chemical supplier.
Last Update:2024-04-09 21:11:58