tert-Butyl 6-(Chlorocarbonyl)-1H-indole-1-carboxylate

tert-Butyl 6-(Chlorocarbonyl)-1H-indole-1-carboxylate - Names and Identifiers

Name	1H-Indole-6-carbonylchloride
Synonyms	1H-Indole-6-carbonylchloride 1H-Indole-6-carbonyl chloride 1-Boc-Indole-6-carbonyl chloride 1H-Indole-6-carbonyl chloride (9CI) tert-Butyl 6-(Chlorocarbonyl)-1H-indole-1-carboxylate 1-Boc-Indole-6-carbonyl chloride (sold and boc protected forM)
CAS	215941-02-9

tert-Butyl 6-(Chlorocarbonyl)-1H-indole-1-carboxylate - Physico-chemical Properties

Molecular Formula	C9H6ClNO
Molar Mass	179.6
Storage Condition	Room Temprature

tert-Butyl 6-(Chlorocarbonyl)-1H-indole-1-carboxylate - Introduction

It is an organic compound with the chemical formula C9H6ClNO. Its nature is as follows:

1. Appearance: White or light yellow solid.
2. Melting Point: about 76-80 ° C.
3. Boiling Point: about 343-350 ° C.
4. Solubility: Soluble in organic solvents such as ether, dimethylformamide, dichloromethane, etc., insoluble in water.
5. Precautions: Irritating to skin and glasses, avoid direct contact.

In practical applications, the main uses of the pill include:

1. Chemical synthesis intermediates: can be used as organic synthesis intermediates for the synthesis of other similar compounds. For example, it can be used to construct the backbone of an indole compound.
2. Drug research: It has the structural characteristics of natural product indolone, so it can be used to prepare new drug molecules.
3. Pesticide research: Its derivatives can show insecticidal activity, so it can be used in the field of pesticide research.

The preparation method of lithium mainly has the following:

1. Chemical synthesis: obtained by reacting indole with chlorinated acid chloride.
2. Acid-base neutralization: reaction of 6-carbonyl indole with chloro aluminous acid, and neutralization of acid-base to obtain carbonyl chloro-1H-indole.

Use should pay attention to safety matters:

1. Comply with laboratory practices and wear protective gloves and glasses.
2. Avoid contact with skin and eyes, if accidentally come into contact with, please immediately rinse with plenty of water, and seek the help of a doctor.
3. Avoid inhalation of its dust or steam, use to maintain good ventilation.
4. Store to keep sealed, away from the fire and oxidant.

Last Update：2024-04-09 20:49:11