Name | stevioside |
Synonyms | steviosin stevioside Stevia Sugar beta-d-glucopyranosylester kaur-16-en-18-oicacid,13-((2-o-beta-d-glucopyranosyl-alpha-d-glucopyranosyl)o (4alpha)-beta-d-glucopyranosyl 13-[(2-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]kaur-16-en-18-oate 13-[(2-O-beta-D-Glucopyranosyl-alpha-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid beta-D-glucopyranosyl ester 1-O-{(5beta,8alpha,9beta,10alpha,13alpha)-13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxokaur-16-en-18-yl}-beta-D-glucopyranose 1-O-[(5beta,8alpha,9beta,10alpha,13alpha)-13-{[2-O-(beta-D-Glucopyranosyl)-beta-D-glucopyranosyl]oxy}-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose 1-O-[(5bêta,8alpha,9bêta,10alpha,13alpha)-13-{[2-O-(bêta-D-Glucopyranosyl)-bêta-D-glucopyranosyl]oxy}-18-oxokaur-16-én-18-yl]-bêta-D-glucopyranose beta-d-glucopyranosyl(1r,4as,7s,8ar,10as)-7-(2-o-(beta-d-glucopyranosyl)-alpha-d-glucopyranosyloxy)-1,4a-dimethyl-12-methyleneperhydro-7,8a-ethanophenanthren-1-carboxylate (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl-(1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5,9-dimethyl-14-methylentetracyclo[11.2.1.0~1,10~.0~4,9~]hexadecan-5-carboxylat (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5,9-dimethyl-14-methylenetetracyclo[11.2.1.0~1,10~.0~4,9~]hexadecane-5-carboxylate (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-2-yl]oxy}-5,9-diméthyl-14-méthylènetétracyclo[11.2.1.0~1,10~.0~4,9~]hexadécane-5-carboxylate de (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yle |
CAS | 57817-89-7 |
EINECS | 260-975-5 |
InChI | InChI=1/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+/m1/s1 |
InChIKey | ZBXJPXVJLBZBLI-IJGGXEOMSA-N |
Molecular Formula | C38H60O18 |
Molar Mass | 804.88 |
Density | 1.53±0.1 g/cm3(Predicted) |
Melting Point | 198°C |
Boling Point | 963.3±65.0 °C(Predicted) |
Specific Rotation(α) | D25 -39.3° (c = 5.7 in H2O) |
Flash Point | 290.3°C |
Solubility | Soluble in water |
Vapor Presure | 0mmHg at 25°C |
Appearance | White to yellowish crystalline powder |
Color | white |
Merck | 14,8810 |
pKa | 12.51±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Sensitive | Easily absorbing moisture |
Refractive Index | -39.3 ° (C=6, H2O) |
MDL | MFCD00079561 |
Physical and Chemical Properties | White to yellowish crystalline powder. Melting Point 198 °c. 1g of the product is soluble in 800ml water, ethanol-soluble. The optical rotation [α]20/D was -39.3 °(C = 5.7,H2O). Quickly wet in the air. High temperature, in acidic and alkaline solution is relatively stable. |
Use | Used as a food flavor agent, especially suitable for hypertension, diabetes, obesity, heart disease, dental caries, etc |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | NZ8175000 |
HS Code | 29389090 |
Reference Show more | 1. Yan Zhen, ni Jiyun, Li Zhixia, etc. Simultaneous determination of seven sweeteners in fruit juice by ultra performance liquid chromatography-tandem mass spectrometry [J]. Quality and safety of agricultural products, 2018, 000(004):25-30,39. 2. Jin Lei, Zhu Jingchao, Zhang Zeyu, Zheng Pinghan, Wang Hui, Kai Guo Yin, Zhang water conservancy, Yuan Qiang, Xi Ning. Optimization of preparation technology of Cornus officinalis yam jelly by Central composite design response surface methodology [J]. China Modern Applied Pharmacy, 2021,38(04):385-390. 3. [IF = 4.508] Qiwei Xu et al."Recovery of rebaudioside A from mother liquor sugar in industrial steviol glycoside production by adding inorganic salts." Sustain Chem Pharm. 2021 May;20:100360 |
colorless crystal or white crystalline powder, odorless, strong sweet taste, sweet pure, sweetness is about 300 times of sucrose. Easy to absorb moisture in the air, soluble in water and ethanol. The heat-resistant, acid-resistant and alkaline properties are good, and there is no change in the solution with pH value of 4~10 after heating for 24 hours.
extracted from stevia, refined.
This product is a mixture of glycosides based on steviol. The content of steviol (c38hfido 18) shall not be less than 95.0% calculated on a dry basis.
take this product, precision weighing, add water to dissolve and quantitatively dilute the solution containing 10.0 mg per lm l (if the solution is not clear, should be filtered). At 25°C, measured by law (General rule 0621 ) , the specific rotation should be -30 ° to -40 °.
is a natural low-calorie sweetener. The calorific value of Stevia sugar is only 300/1 of sucrose, which is not absorbed by the human body and does not produce heat. It is a sweetener suitable for patients with diabetes and obesity. When stevia is mixed with sucrose fructose or isomerized sugar, it can increase its sweetness and improve taste. Can be used for candy, cakes, beverages, solid drinks, fried foods, spices, preserved fruit. According to the production needs of appropriate use.
10mg of this product and 10mg of steviol reference substance were respectively dissolved by adding anhydrous ethanol lm l to prepare the test solution and the reference solution. According to the thin layer chromatography (General 0502) test, absorb the above two solutions 1, respectively, on the same silica gel G thin layer plate, with chloroform-methanol-water (65 : 35 : 10) the lower layer of liquid as the developer, expand, take out, dry, spray with 30% sulfuric acid ethanol solution, heated at 110°C for about 15 minutes to clear spots, the position of the main spot displayed by the test solution should be the same as that of the control solution.
take this product, precision weighing, adding water to dissolve and quantitatively dilute to make a solution containing 20.0 mg per lm l. UV-visible spectrophotometry (General 0401) at the wavelength of 370mn, absorbance should not be greater than 0. 10.
take 0.50g of this product, add 20ml of neutral ethanol (neutral to phenolphthalein indicator solution), shake to dissolve, add 1 drop of phenolphthalein indicator solution, and use sodium hydroxide titration solution (0. lm o l/L) titrated to red color and did not fade in 10 seconds, consuming sodium hydroxide titration solution (0. lm o l/L) must not pass 0. 5ml.
take this product, dry to constant weight at 105°C, weight loss shall not exceed 5.0% (General rule 0831).
The l.O g of this product shall be taken for inspection according to law (General rule 0841), and the remaining residue shall not exceed.
The residue left under the item of burning and flooding shall not contain more than 20 parts per million of heavy metals for examination by law (General rule 0821, Law II).
take this product l.O g, add 10ml nitric acid to infiltrate the sample, place for a moment, add several glass beads, slowly heat, after the effect is relieved, slightly cold, add 5ml sulfuric acid along the bottle wall, then slowly heat, the solution in the bottle began to turn red-brown, keep slightly boiling, and added 2-3ml of nitric acid Dropwise, every time, until the solution was colorless or light yellow, continued to heat for 5 minutes, cooled, and added 10ml of water, boil to produce white smoke, cool, slowly add appropriate amount of water to make 0822, according to law inspection (General Principles 0.0002% the first law), should comply with the provisions ().
take this product about 0 .3G, precision weighing, 250ml Erlenmeyer flask, add dilute sulfuric acid 2 5ml and water 25ml, shake dissolved, heated to micro boiling, hydrolysis for 30 minutes, cooling, filtering, after washing the residue with water until neutral, add 50ml of neutral ethanol (neutral to phenolphthalein indicator solution), dissolve it, add 2 drops of phenolphthalein indicator solution, and make potassium hydroxide titration solution (0. 05inOl/L) titration to the solution is red, 10 seconds does not fade. Each l of ethanol to potassium hydroxide titrant (0.05 mol/L) corresponds to 40. 24mg of C38H60O18.
pharmaceutical excipients, flavors and sweeteners.
sealed storage.