Name | spectinomycin |
Synonyms | spectam spectinomycin spectinomicina spectinomycine actinospectacin espectinomicina antibiotic2233wp actinospectacina 8-bis(methylamino)- 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dihydrochloride |
CAS | 1695-77-8 |
EINECS | 216-911-3 |
InChI | InChI=1/C14H24N2O7.ClH/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;/h5,7-13,15-16,18-20H,4H2,1-3H3;1H/t5-,7-,8+,9+,10+,11-,12-,13+,14+;/m1./s1 |
Molecular Formula | C14H24N2O7 |
Molar Mass | 332.35 |
Density | 1.43±0.1 g/cm3(Predicted) |
Melting Point | 185 °C (decomp) |
Boling Point | 583.1±50.0 °C(Predicted) |
Specific Rotation(α) | D25 -20° (water) |
Flash Point | 306.4°C |
Vapor Presure | 5.05E-16mmHg at 25°C |
pKa | pKa1 6.95, pKa2 8.70(at 25℃) |
Physical and Chemical Properties | Spectinomycin is an alkaline antibiotic, the stronger the alkaline, the stronger its antibacterial effect; But spectinomycin is not soluble in water, so it is often used in clinic as its hydrochloride, white or white crystalline powder, soluble in water. The aqueous solution dissolved in water was acidic, and the PH of the 1% aqueous solution was 3.8-5.6. |