Name | pyrrole |
Synonyms | Azole Pyrrol Parzate Pyrrhol PYRROLE Imidole pyrrole HSDB 119 AI3-18817 NSC 62777 CCRIS 2933 1H-Pyrrole Monopyrrole FEMA No. 3386 Divinylenimine Divinyleneimine UNII-86S1ZD6L2C 1-Aza-2,4-cyclopentadiene 4-methyl(di-pyrrol-2-yl-methtyl)pyridinium iodide |
CAS | 109-97-7 |
EINECS | 203-724-7 |
InChI | InChI=1/C4H5N/c1-2-4-5-3-1/h1-5H |
InChIKey | KAESVJOAVNADME-UHFFFAOYSA-N |
Molecular Formula | C4H5N |
Molar Mass | 67.09 |
Density | 0.967 g/mL at 25 °C (lit.) |
Melting Point | -23 °C (lit.) |
Boling Point | 131 °C (lit.) |
Flash Point | 92°F |
JECFA Number | 1314 |
Water Solubility | 60 g/L (20 ºC) |
Solubility | 60g/l |
Vapor Presure | 8.7 hPa (20 °C) |
Vapor Density | 2.31 (vs air) |
Appearance | Liquid |
Color | Clear almost colorless to brownish |
Merck | 14,8014 |
BRN | 1159 |
pKa | 15(at 25℃) |
PH | >6 (10g/l, H2O, 20℃) |
Storage Condition | Store at +2°C to +8°C. |
Stability | Stable. Incompatible with strong acids, strong oxidizing agents. Combustible. |
Sensitive | Air & Light Sensitive |
Explosive Limit | 3.10-14.8%(V) |
Refractive Index | n20/D 1.508(lit.) |
Physical and Chemical Properties | Density 0.967 melting point -23°C boiling point 129-131°C refractive index 1.508-1.51 flash point 36°C water-soluble 60g/L (20°C) |
Use | For the synthesis of fine chemicals such as pharmaceuticals and spices |
Hazard Symbols | T - Toxic |
Risk Codes | R10 - Flammable R20 - Harmful by inhalation R25 - Toxic if swallowed R41 - Risk of serious damage to eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. S24 - Avoid contact with skin. S16 - Keep away from sources of ignition. |
UN IDs | UN 1992 3/PG 3 |
WGK Germany | 2 |
RTECS | UX9275000 |
FLUKA BRAND F CODES | 8-10-23 |
TSCA | Yes |
HS Code | 29339900 |
Hazard Class | 3 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 137 mg/kg |
Raw Materials | Furan Ammonia |
Downstream Products | 2-acetylpyrrole |
light yellow or brown oily liquid with a chloroform-like odor. Melting Point -24 °c. Boiling point 129 °c. Relative density (water 1),0. 97. Relative vapor density (Air 1),2.31. Heat of combustion 2373.okj/mol. Flash point 39 °c. Slightly soluble in water, soluble in ethanol, ether and other organic solvents.
with furan and ammonia as raw materials, Y-alumina as catalyst, obtained by gas phase catalytic reaction. It can also be prepared by reacting 1,4-butynediol with ammonia.
used as a standard substance for chromatographic analysis, and also used in organic synthesis and pharmaceutical industry. Pyrrole is widely used in the synthesis of pharmaceuticals, pesticides and dyes. In the pharmaceutical industry can be used for the synthesis of iloxacin (irloxacin), pyrrolimidic acid (piromidic), pyrrolidone (pyrovalerone), pyrrocaine (pyrrocaine) and disease control (TMT) et al.
Toxicity: LD50(mg/kg): Rat oral 61. Health hazards: inhalation of vapor can cause anesthesia, and can cause body temperature continued to increase. Explosion hazard: This product is flammable and irritating. Hazard characteristics: its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of open flame and high heat energy. A reaction with an oxidizing agent may occur. High temperature decomposition, the release of highly toxic nitrogen oxide gas. The flow rate is too fast, easy to generate and accumulate static electricity. It is easy to self-polymerize, and the polymerization reaction rapidly increases with the increase of temperature. Its vapor is heavier than air, and it can diffuse to a relatively far place at a lower place, and it will fire and burn back in case of a fire source. In case of high fever, the internal pressure of the container increases, and there is a risk of cracking and explosion.