methyl4-chloro-6-methylquinoline-2-carboxylate is an organic compound with the chemical formula C12H11ClNO2. The following is information about the properties, use, preparation and safety of the compound:
Nature:
-Appearance: Colorless to light yellow solid
-melting point: 62-64 ℃
-Melting point range: 2-4 ℃
-Molecular weight: 243.68g/mol
-Solubility: Soluble in organic solvents such as chloroform and dimethylformamide
Use:
methyl4-chloro-6-methylquinoline-2-carboxylate is commonly used as an intermediate in organic synthesis and is widely used in the fields of medicine and pesticide. It can be used to synthesize organic compounds containing quinoline structure, such as drugs, pesticides and other biologically active molecules.
Method:
methyl4-chloro-6-methylquinoline-2-carboxylate can be synthesized by the following steps:
1. first 4-chloro -6-methyl -2-quinolinone and formic acid reaction, the corresponding acid.
2. Then, use thionyl chloride and triethylamine to condense the acid with methanol at an appropriate temperature to produce the final esterification product.
Safety Information:
methyl4-chloro-6-methylquinoline-2-carboxylate may be toxic to the human body, so when operating, you need to pay attention to personal protective measures, such as wearing gloves, glasses and protective clothing. Contact with skin and eyes should be avoided. It is necessary to carry out the operation in a well-ventilated place and avoid inhaling the dust or vapor of the compound. Special attention should be paid to proper storage and disposal of the compound to avoid environmental pollution or harm to human health. Before use, please read the safety data sheet of the compound carefully and follow the corresponding operating instructions.