ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate - Names and Identifiers
ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate - Introduction
ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate is an organic compound. Its chemical formula is C9H10F2NO3, and its relative molecular mass is 221.18g/mol. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate is a colorless to light yellow liquid.
-Melting point and boiling point: Its melting point is -50 ° C, and the boiling point is 140-142 ° C.
-Solubility: It is soluble in organic solvents such as ethanol, ether and dichloromethane.
Use:
- ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate is often used as a reagent in organic synthesis, especially in pharmaceutical research and development.
-This compound can also be used for the synthesis of biochemical markers, pharmaceutical intermediates and pesticides.
Method:
The preparation method of ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate includes the following steps:
1. Reacting 3-methoxypyridine with hydrofluoric acid to generate fluoride of 3-methoxypyridine;
2. React the generated fluoride with ethyl acetate to obtain ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate.
Safety Information:
- ethyl 2,2-difluoro-2-(3-methoxypyridin-2-yl)acetate is an organic compound that should be handled with caution and avoid contact with skin, eyes and respiratory tract.
-Wear appropriate protective equipment such as gloves, goggles and protective masks when used.
-Avoid contact with strong oxidants and strong acids to prevent dangerous reactions.
-When performing laboratory operations, it should be carried out in a well-ventilated place to avoid the formation of high concentrations of steam and gas.
Last Update：2024-04-09 02:00:51