Molecular Formula | C9H9N3O2 |
Molar Mass | 191.19 |
Density | 1.4500 |
Melting Point | >300 °C (lit.) |
Boling Point | 326.92°C (rough estimate) |
Flash Point | 11°C |
Solubility | Insoluble in water and general organic solvents, the solubility (mass ratio) at 20°C is: acetone 0 · 04%, ethanol 0 · 03%, chloroform 0 · 01%, benzene, ether and water are all less than 0 · 001%. Soluble in organic acids such as sulfuric acid, hydrochloric acid and acetic acid, and form corresponding salts. It is more stable to heat and acid |
Vapor Presure | 1.5 x 10-4 Pa (25 °C) |
Appearance | The pure product is white crystal, and the industrial product is light yellowish brown powder. |
Merck | 13,1799 |
BRN | 649044 |
pKa | 4.48(at 25℃) |
Storage Condition | -20°C |
Refractive Index | 1.6500 (estimate) |
MDL | MFCD00055390 |
Physical and Chemical Properties | White crystalline powder. Sublimation began at 216-217 ℃. Melting point 307~312 °c (decomposition). Density 1.45±0.05g/cm3(20 degrees C), vapor pressure 1.3.33 Pa(20 degrees C). Solubility (24 ℃): Water 29(pH 4), 8(pH 7), 7(pH 8)mg/L, hexane 0.5mg/L, benzene 36mg/L, ethanol, acetone 300mg/L, dichloromethane 68mg/L, ethyl acetate 135mg/L. Stable to heat. |
Use | Can control peanut leaf spot, black spot, Triticum aestivum scab, Sclerotinia sclerotiorum, rice sheath blight, citrus canker and so on. |
Risk Codes | R46 - May cause heritable genetic damage R60 - May impair fertility R61 - May cause harm to the unborn child R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
UN IDs | UN 3077 9/PG 3 |
WGK Germany | 3 |
RTECS | DD6500000 |
HS Code | 29339900 |
Toxicity | LD50 oral in rabbit: 8160mg/kg |
Downstream Products | Benomyl |
Reference Show more | 1. Xiao Suping, Zhong Rongrong, Gao Hui, et al. Rapid Determination of Eight Pesticide Residues in Different Dendrobium by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry [J]. Modern Chinese Medicine, 2020, v.22(04):135-140 153. 2. Liu, Shaoying, et al. "Comparison of extraction solvents and sorbents in the quick, easy, cheap, effective, rugged, and safe method for the determination of pesticide multiresidue in ruits by ultra high performance liquid chromatography with tandem mass s 3. [IF = 3.969] Xu Shiqiang et al." Molecular characterization of carbendazim resistance of Fusarium species complex that problems sugarcane pokkah boeng disease."Bmc Genomics. 2019 Dec;20(1):1-14 |
The Pure product is white crystal, and the industrial product is yellowish brown powder. mp302 ~ 307 C (decomposition);pK. 4.48. Solubility in solvent at 20 ° C. (mg/L): n-hexane 0.5, benzene 36, ethanol 300, chloroform 100, acetone 300. Relatively stable to heat, unstable to acid-base.
methyl chloroformate is synthesized from phosgene and methanol by batch and continuous processes, and then methyl cyanocarbamate is obtained by cyanoammoniation with methyl chloroformate after hydrolysis of ammonia to form cyanamide. Finally, the reaction of O-phenylenediamine with methyl cyanocarbamate yields carbendazim.
carbendazim is a benzimidazole fungicide. High efficiency, low toxicity, broad bactericidal spectrum, long duration, for many ascomycetes, semilynoides and a variety of Basidiomycetes effective, invalid for algae. Carbendazim can be absorbed by plants and transferred to other parts through conduction, which interferes with the mitosis of pathogenic cells and inhibits their growth. For the prevention and control of Triticum aestivum scab, cereal smut, cotton seedling disease, Sclerotinia sclerotiorum, rice sheath blight, rice blast, beet brown spot disease. For the prevention and control of grain, cotton, oil, fruit, vegetables, flowers, a variety of fungal diseases, can also be used for fruit preservation. Generally processed into powders, wettable powders and suspensions are used.
rats, mice by mouth> 5000~15000mg/kg, rat percutaneous LD50>2000mg/kg, rat intraperitoneal injection LD50> 15000mg/kg. The original drug on dogs and rats for three months of feeding, no effect of doses were 500 mg/kg and 400 mg/kg, no carcinogenic, teratogenic and mutagenic effects. Low toxicity to fish and bees, carp LC50 40mg/L(48h).