Vildagliptin Impurity 48

Vildagliptin Impurity 48 - Names and Identifiers

Name	2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)
Synonyms	Vildagliptin Impurity 48 1-Glycoloyl-L-prolinamide 1-glycoloyl-L-proline amide Vildagliptin Impurity -01 VN-01 (S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide (S)-1-(2-hydroxyacetyl)pyrrolidine-2-carboxamide 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)
CAS	96166-39-1

Vildagliptin Impurity 48 - Physico-chemical Properties

Molecular Formula	C7H12N2O3
Molar Mass	172.18
Density	1.356±0.06 g/cm3(Predicted)
Boling Point	484.2±45.0 °C(Predicted)
pKa	13.58±0.10(Predicted)
Storage Condition	2-8°C

Vildagliptin Impurity 48 - Introduction

2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) is an organic compound with the chemical formula C8H14N2O3.

Nature:
-Appearance: Colorless to slightly yellow solid
-Melting Point: about 110-112 ℃
-Solubility: Soluble in water and ethanol

Use:
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) is a synthetic intermediate compound. It can be used in organic synthesis reactions, such as synthetic drugs, natural products or organic heterocyclic compounds.

Preparation Method:
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) has many preparation methods, one of which is synthesized by amidation reaction. The specific steps are as follows:
1. Take 2-pyrrole carboxylic acid (acid) and hydroxyacetic acid ester as raw materials.
2. The raw materials are reacted by heating in an appropriate solvent to generate the target compound 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI).
3. After the reaction, the pure product can be obtained by crystallization or other process methods.

Safety Information:
No specific safety information is currently reported for 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI). But as a chemical, it has general chemical safety and protection requirements. Wear appropriate personal protective equipment, such as chemical safety glasses, protective gloves and laboratory clothing. In addition, laboratory safety procedures should be followed and adequate ventilation should be provided. If necessary, it should be operated in a specialized laboratory environment, following relevant regulations and safety standards. When using or disposing of this compound, it is important to follow relevant government and agency regulations and guidelines. If any discomfort or accident occurs, seek medical attention immediately.

Last Update：2024-04-09 20:52:54