Uridine 5-diphosphoric acid disodium salt (UDP)
uridine 5'-diphosphate disodium salt
CAS: 27821-45-0
Molecular Formula: C15H24N2Na2O18P2
Uridine 5-diphosphoric acid disodium salt (UDP) - Names and Identifiers
| Name | uridine 5'-diphosphate disodium salt |
| Synonyms | UDP 2NA 5'-UDP-Na2 UDP(URIDINE-5''-DIPHOSPHATE) Uridine 5'-diphosphate disodiu salt uridine 5'-diphosphate disodium salt Uridine-5'-diphosphate disodium salt URIDINE 5'-DIPHOSPHATE DISODIUM SALT Uridine-5'-diphosphate disodium(UDP) Uriidine-5'-diphosphate,disodium salt Diquafosol Impurity 2(UDP Sodium Salt) URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT Uridine 5'-diphosphoric acid disodium salt Uridine 5-diphosphoric acid disodium salt (UDP) Uridine 5'-(trihydrogen diphosphate), disodium salt disodium 1-{5-O-[hydroxy(phosphonatooxy)phosphoryl]-beta-D-glycero-pentofuranosyl}pyrimidine-2,4(1H,3H)-dione |
| CAS | 27821-45-0 |
| EINECS | 248-678-9 |
| InChI | InChI=1/C9H14N2O12P2.2Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6?,7?,8-;;/m1../s1 |
| InChIKey | KWDGQJWFEYTPBN-IBOJMDDDSA-L |
Uridine 5-diphosphoric acid disodium salt (UDP) - Physico-chemical Properties
| Molecular Formula | C15H24N2Na2O18P2 |
| Molar Mass | 628.28 |
| Water Solubility | Slightly soluble in water. |
| Solubility | Easily soluble in water, insoluble in ethanol. |
| Appearance | White fine crystal |
| Color | White to Off-white |
| BRN | 8817400 |
| Storage Condition | -20°C |
| Sensitive | Moisture Sensitive |
| MDL | MFCD00149253 |
| Physical and Chemical Properties | Properties: uridine disodium diphosphate is white powder, soluble in water, insoluble in ethanol. A250/A260 = 0.75±0.05; A280/A260 = 0.38±0.05; Λmax = 262±1nm at pH 2. This product can be used as pharmaceutical and chemical intermediates and biochemical reagents. |
Uridine 5-diphosphoric acid disodium salt (UDP) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29349990 |
Uridine 5-diphosphoric acid disodium salt (UDP) - Reference Information
| Uses | Uridine -5 '-disodium diphosphate salt is an organometallic compound, which can be used as a biochemical reagent. It is a P2Y6 receptor agonist and GPR105 receptor inhibitor. |
| application | uridine -5 '-disodium diphosphate salt can be used as a biochemical reagent, P2Y receptor agonist. |
| biological activity | Uridine-5 '-diphosphate (UDP) disodium salt is an effective and selective P2Y6 receptor natural agonist with an EC50 value of 300 nM and a pEC50 value of 6.52. Uridine-5 '-diphosphate (UDP) disodium salt is also an antagonist of P2Y14 receptor with a pEC50 value of 7.28. |
| Target | Value |
| P2Y 14 receptor (Cell-free assay) | 7.28(pEC50) |
| P2Y 6 receptor (Cell-free assay) | 300 nM(EC50) 6.52(pEC50) |
| Cell Line: | Primary microglia |
| Concentration: | 100 μM |
| Incubation Time: | For 15 min |
| Result: | Significantly induced microglial CCL2 and CCL3 mRNA expression. |
Last Update：2024-04-10 22:29:15
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View History
Uridine 5-diphosphoric acid disodium salt (UDP)
1alpha-Hydroxyvitamin D4
SOTALOL
3-Amino-1H-pyrazole-4-carboxamide Hemisulfate
METHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-5-CARBOXYLATE
(R)-(+)-2-(4-Hydroxy Phenoxy)propionic acid
richloro(trichlorosilylmethyl)silane
2-CHLORO-3-NITROTHIOPHENE-5-SULFONYL CHLORIDE
1alpha-Hydroxyvitamin D4
SOTALOL
3-Amino-1H-pyrazole-4-carboxamide Hemisulfate
METHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-5-CARBOXYLATE
(R)-(+)-2-(4-Hydroxy Phenoxy)propionic acid
richloro(trichlorosilylmethyl)silane
2-CHLORO-3-NITROTHIOPHENE-5-SULFONYL CHLORIDE