TERT-BUTYL (R)-(1-(3-CHLOROPHENYL)-2-HYDROXYETHYL)CARBAMATE
Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
CAS: 926291-64-7
Molecular Formula: C13H18ClNO3
TERT-BUTYL (R)-(1-(3-CHLOROPHENYL)-2-HYDROXYETHYL)CARBAMATE - Names and Identifiers
TERT-BUTYL (R)-(1-(3-CHLOROPHENYL)-2-HYDROXYETHYL)CARBAMATE - Physico-chemical Properties
| Molecular Formula | C13H18ClNO3 |
| Molar Mass | 271.74 |
| Storage Condition | 2-8°C |
TERT-BUTYL (R)-(1-(3-CHLOROPHENYL)-2-HYDROXYETHYL)CARBAMATE - Introduction
Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester, chemical name is Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, a common abbreviation of organic Boc-ClBn.
Nature:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester is a colorless to pale yellow liquid that is stable at room temperature. It has low volatility and moderate solubility, and is easily soluble in organic solvents. This compound has hydroxyl and amino functional groups, while chloro and benzyl groups are also present.
Use:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester are commonly used as intermediates in organic synthesis. It can be used to prepare drugs or compounds with biological activity, such as chiral drugs, new generation pesticides, etc.
Method:
The preparation method of Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester is usually carried out by chemical synthesis. The following is a possible synthesis method:
First, 3-chlorophenylethyl alcohol is reacted with sodium hydroxide to produce 3-chlorophenylethyl sodium salt. The resulting sodium salt is then reacted with Boc-amino p-toluenesulfonate to produce Boc-amino-3-chlorophenethanol. Finally, the Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester, was generated by alcoholation of the resulting Boc-amino-3-chlorophenylethyl alcohol using an appropriate organic solvent and catalyzed by the addition of trimethylboronic acid and tert-butyl carbonate.
Safety Information:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester is an organic compound, which should be handled safely when using. It may be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment when handling and handling, and ensure that it is carried out in a well-ventilated environment. This compound has low toxicity, but medical help should be sought immediately if ingestion or exposure occurs. When storing, it should be kept in a cool, dry, ventilated place, away from fire and oxidant.
Nature:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester is a colorless to pale yellow liquid that is stable at room temperature. It has low volatility and moderate solubility, and is easily soluble in organic solvents. This compound has hydroxyl and amino functional groups, while chloro and benzyl groups are also present.
Use:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester are commonly used as intermediates in organic synthesis. It can be used to prepare drugs or compounds with biological activity, such as chiral drugs, new generation pesticides, etc.
Method:
The preparation method of Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester is usually carried out by chemical synthesis. The following is a possible synthesis method:
First, 3-chlorophenylethyl alcohol is reacted with sodium hydroxide to produce 3-chlorophenylethyl sodium salt. The resulting sodium salt is then reacted with Boc-amino p-toluenesulfonate to produce Boc-amino-3-chlorophenethanol. Finally, the Carbamic acid, N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester, was generated by alcoholation of the resulting Boc-amino-3-chlorophenylethyl alcohol using an appropriate organic solvent and catalyzed by the addition of trimethylboronic acid and tert-butyl carbonate.
Safety Information:
Carbamic acid, N-[(1R)-1-(3-chlorophyll)-2-hydroxyethyl]-, 1,1-dimethyl ester is an organic compound, which should be handled safely when using. It may be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment when handling and handling, and ensure that it is carried out in a well-ventilated environment. This compound has low toxicity, but medical help should be sought immediately if ingestion or exposure occurs. When storing, it should be kept in a cool, dry, ventilated place, away from fire and oxidant.
Last Update：2024-04-09 21:01:54
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View History
TERT-BUTYL (R)-(1-(3-CHLOROPHENYL)-2-HYDROXYETHYL)CARBAMATE
2-甲基-3-氨基异烟酸甲酯
2H-Azepin-2-one, hexahydro-, polymer with 1,2-ethanediol and 5-isocyanato-1-(isocyanatomethyl) -1,3,3-trimethylcyclohexane
N-[(1-ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)methyl]-1,4-dimethyl-1H-pyrazol-5-amine
Ethanone, 1-[3-[4-[4-(trifluoromethyl)phenyl]-1-piperazinyl]-1-azetidinyl]-
Methacrylic acid 2-[(chlorocarbonyl)oxy]ethyl ester
4-(N-Boc-氨甲基)苯胺
异氰酸1-萘基酯
2-甲基-3-氨基异烟酸甲酯
2H-Azepin-2-one, hexahydro-, polymer with 1,2-ethanediol and 5-isocyanato-1-(isocyanatomethyl) -1,3,3-trimethylcyclohexane
N-[(1-ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)methyl]-1,4-dimethyl-1H-pyrazol-5-amine
Ethanone, 1-[3-[4-[4-(trifluoromethyl)phenyl]-1-piperazinyl]-1-azetidinyl]-
Methacrylic acid 2-[(chlorocarbonyl)oxy]ethyl ester
4-(N-Boc-氨甲基)苯胺
异氰酸1-萘基酯