Sodium pyruvate
Pyruvic acid, sodium salt
CAS: 113-24-6
Molecular Formula: C3H3NaO3
Sodium pyruvate - Names and Identifiers
| Name | Pyruvic acid, sodium salt |
| Synonyms | Sodium pyruate Sodium pyruvate SODIUM PYRUVATE SodiuM Pyruvate IH pyruvic acid sodium Pyruvic Acid Na-Salt Sodium 2-Oxopropanoate Sodium 2-Oxopropionate sodium-2-ketopropionate Sodium-2-Ketopropionate Pyruvic acid sodium salt pyruvate solution sodium Pyruvic acid, sodium salt Sodium Alpha-Ketopropionate SODIUM ALPHA-KETOPROPIONATE 2-Oxo-Propanoicacisodiumsalt pyruvic acid hybri-max sodium Phenylpyruvic acid Sodium salt 2-OXOPROPANOIC ACID SODIUM SALT 2-KETOPROPIONIC ACID SODIUM SALT |
| CAS | 113-24-6 |
| EINECS | 204-024-4 |
| InChI | InChI=1/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1 |
| InChIKey | DAEPDZWVDSPTHF-UHFFFAOYSA-M |
Sodium pyruvate - Physico-chemical Properties
| Molecular Formula | C3H3NaO3 |
| Molar Mass | 110.04 |
| Density | 1,267g/cm |
| Melting Point | >300 °C (lit.) |
| Boling Point | >300℃ |
| Flash Point | 54.3°C |
| Water Solubility | Soluble in water. |
| Solubility | Soluble in water, solubility in water: 47g/100 ml (20°C), very slightly soluble in alcohol. |
| Vapor Presure | 0Pa at 20℃ |
| Appearance | White powder |
| Color | White to Pale Yellow |
| BRN | 3568341 |
| PH | pH(100g/l, 25℃) : 4.0～8.0 |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Sensitive to heat |
| Refractive Index | 1,426-1,43 |
| MDL | MFCD00002586 |
| Use | Pharmaceutical raw materials and food additives |
Sodium pyruvate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29183000 |
Sodium pyruvate - Upstream Downstream Industry
| Downstream Products | DL-Tartaric Acid Pyruvic acid Pyruvic acid Potassium bisulfate Potassium bisulfate Calcium carbonate Calcium carbonate Ethyl Alcohol |
Sodium pyruvate - Reference
| Reference Show more | 1. [IF=3.267] Zhen-Hong Xia et al."The Underlying Mechanisms of Curcumin Inhibition of Hyperglycemia and Hyperlipidemia in Rats Fed a High-Fat Diet Combined With STZ Treatment."Molecules. 2020 Jan;25(2):271 |
Sodium pyruvate - Nature
Open Data Verified Data
White Flake crystal or powder. mp205 °c. Soluble in water, slightly soluble in ethanol, ether, acetic acid.
Last Update：2024-01-02 23:10:35
Sodium pyruvate - Preparation Method
Open Data Verified Data
pyruvic acid was dissolved in water, and sodium hydroxide was added to neutralize the reaction, and ethanol was added to precipitate sodium pyruvate crystals.
Last Update：2022-01-01 09:26:40
Sodium pyruvate - Use
Open Data Verified Data
biochemical reagents. A reagent for the determination of the content of glutamic-pyruvic transaminase or glutamic-oxaloacetic transaminase in human blood.
Last Update：2022-01-01 09:26:40
Sodium pyruvate - Reference Information
| LogP | -3.83 at 20℃ |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| appearance | sodium pyruvate is white or white-like crystalline powder. |
| solubility | sodium pyruvate is easily soluble in water and slightly soluble in ethanol. |
| effect | sodium pyruvate is necessary to provoke you to carry out metabolic life activities in the daily life of the human body. it is an energy substance. in the cell culture experiment conducted by scientific research, scientific researchers also found similar substances, similar to the substances that participate in the body's metabolic activities and provide energy for the human body, there are glucose, sodium lactate, etc. In the human body, most cells only use glucose, and sodium pyruvate is a necessary substance in cell culture. Sodium pyruvate acts as an alternative carbon source in the culture medium and participates in cellular nutrient metabolism. |
| application | sodium pyruvate is often used in cell culture medium as a source of energy. In addition, Giandomenico et al. found that sodium pyruvate can also protect cells from hydrogen peroxide damage, which has been confirmed by many other teams. |
| preparation | place the pyruvate acid received in the workshop for more than one hour, wrap the nozzle with clean polyester fiber cloth, slowly insert it into the bottom of the barrel, pump 280kg of pyruvate acid into the sodium pyruvate reaction tank with vacuum, after pumping, stirring, stirring, slowly press the pretreated sodium carbonate solution at 38~42 ℃ into the reaction tank (control pressure is 0.03~0.06MPa), and control the temperature in the reaction tank not to exceed 35 ℃ (if the temperature exceeds 35 ℃ during the reaction process, cooling measures should be taken). pH value detection should be carried out during the reaction process, and feeding should be stopped when the pH value of the reaction solution reaches 4.8~5.3 (measured with precision test paper), control the feeding time for about 1 hour. After the reaction is completed, slowly pump the 1440kg 95% ethanol into the reaction tank (the nozzle shall be wrapped with clean polyester fiber cloth) (the adding speed shall be slow first and then fast, the 50% amount adding time shall be controlled within 60 minutes, and the 50% amount adding time shall be controlled within 30 minutes). After the extraction is completed, the ethanol shall be centrifuged and dried, put into a special stainless steel barrel and sent to the drying room, poured into a double cone vacuum drying oven, when the vacuum degree is controlled to be ≥-0.09Mpa, the hot water temperature is 75~80 ℃, and the internal temperature of the vacuum dryer rises to 65 ℃, the baking time is recorded, the internal temperature of the vacuum dryer is controlled to be 65~70 ℃, and the temperature is kept warm for 2 hours. After baking for 2 hours, please check, dry loss ≤ 0.5%, cool for about 20 minutes, discharge, screen with 20 mesh, pack and put into storage. The yield should be between 105±5%. |
| use | used as pharmaceutical raw materials and food additives substrate for determination of lactate dehydrogenase, determination of glutamic-pyruvic transaminase activity in liver function test. |
Last Update：2024-04-09 02:00:06
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Sodium pyruvate
3,11-DICHLORO-6,11-6-METHYLDIBENZO[C,F][1,2]THIAZEPINE5,5-DIOXIDE
N-(1-(3-(1H-IMIDAZOL-1-YL)PROPYLAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-2-(4-METHOXYBENZAMIDO)BENZAMIDE
3,11-DICHLORO-6,11-6-METHYLDIBENZO[C,F][1,2]THIAZEPINE5,5-DIOXIDE
N-(1-(3-(1H-IMIDAZOL-1-YL)PROPYLAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-2-(4-METHOXYBENZAMIDO)BENZAMIDE
Downstream Products for Sodium pyruvate