Molecular Formula | C29H27F3N6O |
Molar Mass | 532.56 |
Density | 1.3 |
Melting Point | >175°C (dec.) |
Solubility | Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming). |
Appearance | Yellow powder. |
Color | Yellow |
pKa | 12.99±0.70(Predicted) |
Storage Condition | -20°C |
Stability | Stable for 2 years from date? of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
Use | Ponatinib (AP24534) is a new and effective multi-target inhibitor acting on Abl, PDGFRα, VEGFR2, FGFR1 and Src. IC50 is 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM respectively. |
HS Code | 29335990 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.878 ml | 9.388 ml | 18.777 ml |
5 mM | 0.376 ml | 1.878 ml | 3.755 ml |
10 mM | 0.188 ml | 0.939 ml | 1.878 ml |
5 mM | 0.038 ml | 0.188 ml | 0.376 ml |