Phenylsuccinic anhydride
Phenylsuccinic anhydride
CAS: 1131-15-3
Molecular Formula: C10H8O3
Phenylsuccinic anhydride - Names and Identifiers
| Name | Phenylsuccinic anhydride |
| Synonyms | Phenylsuccinic anhyd Phenylsuccinic anhydride 3-phenyloxolane-2,5-dione PhenylbutanedioicAnhydride 2-Phenylsuccinic anhydride 3-phenyldihydrofuran-2,5-dione 3-Phenyldihydrofuran-2,5-dione Dihydro-3-phenyl-2,5-furandione 3-Phenyltetrahydrofuran-2,5-dione 3-phenyltetrahydrofuran-2,5-quinone |
| CAS | 1131-15-3 |
| InChI | InChI=1/C10H8O3/c11-9-6-8(10(12)13-9)7-4-2-1-3-5-7/h1-5,8H,6H2 |
Phenylsuccinic anhydride - Physico-chemical Properties
| Molecular Formula | C10H8O3 |
| Molar Mass | 176.17 |
| Density | 1.1958 (rough estimate) |
| Melting Point | 53-55 °C (lit.) |
| Boling Point | 191-192 °C/12 mmHg (lit.) |
| Flash Point | 191-192°C/12mm |
| Solubility | soluble in Methanol |
| Vapor Presure | 3.23E-05mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Orange to Green |
| Storage Condition | Room Temprature |
| Refractive Index | 1.5036 (estimate) |
| MDL | MFCD00192395 |
| Physical and Chemical Properties | Appearance white solid |
| Use | Pharmaceutical Intermediates |
Phenylsuccinic anhydride - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29173995 |
Phenylsuccinic anhydride - Introduction
Phenyl succinic anhydride is an organic compound with the chemical formula C6H5CO2CH2CH2CO2C6H5. It has the following properties:
1. Appearance: Phenyl succinic anhydride is colorless crystal or white crystalline powder.
2. melting point: its melting point range of 57-60 ℃.
3. Solubility: It can be dissolved in many organic solvents, such as alcohols, ethers, ketones and chlorinated hydrocarbons.
4. Reactivity: It can undergo transesterification with many compounds and can be reduced to phenylacetone.
Phenyl succinic anhydride has a wide range of uses in industry, including:
1. Dyes and pigments: It can be used as raw materials for dyes and pigments, and is used in industries such as textiles, plastics and printing.
2. Food additive: It can be used as a food additive to increase the aroma and seasoning of food.
3. pharmaceutical intermediates: it can be used for the synthesis of pharmaceutical intermediates, such as ester drugs and allergens.
The preparation method of phenyl succinic anhydride is generally accomplished by the acylation reaction of benzoic acid and succinic anhydride. First, benzoic acid is reacted with succinic anhydride in an alcohol solvent, a catalyst is added, the reaction is heated for a certain period of time, and then filtered and crystallized to obtain the target product.
When using phenyl succinic anhydride, the following safety precautions should be paid attention:
1. Avoid contact with skin and eyes: Phenyl succinic anhydride is irritating and requires personal protective equipment, such as gloves and goggles, to prevent contact.
2. Avoid inhalation and intake: Try to avoid inhaling aerosols or splashing liquids during operation, and avoid eating by mistake.
3. Storage Note: Phenyl succinic anhydride should be stored in a dry, cool place, away from fire and flammable materials.
1. Appearance: Phenyl succinic anhydride is colorless crystal or white crystalline powder.
2. melting point: its melting point range of 57-60 ℃.
3. Solubility: It can be dissolved in many organic solvents, such as alcohols, ethers, ketones and chlorinated hydrocarbons.
4. Reactivity: It can undergo transesterification with many compounds and can be reduced to phenylacetone.
Phenyl succinic anhydride has a wide range of uses in industry, including:
1. Dyes and pigments: It can be used as raw materials for dyes and pigments, and is used in industries such as textiles, plastics and printing.
2. Food additive: It can be used as a food additive to increase the aroma and seasoning of food.
3. pharmaceutical intermediates: it can be used for the synthesis of pharmaceutical intermediates, such as ester drugs and allergens.
The preparation method of phenyl succinic anhydride is generally accomplished by the acylation reaction of benzoic acid and succinic anhydride. First, benzoic acid is reacted with succinic anhydride in an alcohol solvent, a catalyst is added, the reaction is heated for a certain period of time, and then filtered and crystallized to obtain the target product.
When using phenyl succinic anhydride, the following safety precautions should be paid attention:
1. Avoid contact with skin and eyes: Phenyl succinic anhydride is irritating and requires personal protective equipment, such as gloves and goggles, to prevent contact.
2. Avoid inhalation and intake: Try to avoid inhaling aerosols or splashing liquids during operation, and avoid eating by mistake.
3. Storage Note: Phenyl succinic anhydride should be stored in a dry, cool place, away from fire and flammable materials.
Last Update：2024-04-09 21:21:28
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View History
Phenylsuccinic anhydride
12679-86-6
3(2H)-Pyridazinone, 4-chloro-5-(cyclohexylamino)-2-(2-oxopropyl)-
RNA Polymerase III Inhibitor
22694-65-1
2173194-53-9
85896-43-1
54788-38-4
2-Oxazolamine, 5-bromo-4-(4-methylphenyl)-N-(3-phenyl-2-propen-1-ylidene)-
860789-09-9
12679-86-6
3(2H)-Pyridazinone, 4-chloro-5-(cyclohexylamino)-2-(2-oxopropyl)-
RNA Polymerase III Inhibitor
22694-65-1
2173194-53-9
85896-43-1
54788-38-4
2-Oxazolamine, 5-bromo-4-(4-methylphenyl)-N-(3-phenyl-2-propen-1-ylidene)-
860789-09-9