NSC 47438
Fluorometholone Acetate
CAS: 3801-06-7
Molecular Formula: C24H31FO5
NSC 47438 - Names and Identifiers
NSC 47438 - Physico-chemical Properties
| Molecular Formula | C24H31FO5 |
| Molar Mass | 418.5 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 230-232° |
| Boling Point | 532.1±50.0 °C(Predicted) |
| Specific Rotation(α) | D +28° (chloroform) |
| Flash Point | 275.6°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.53E-13mmHg at 25°C |
| Appearance | Solid |
| Color | Off-White to Light Yellow |
| pKa | 13.01±0.70(Predicted) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.556 |
| Use | Content determination |
| In vitro study | Fluorometholone Acetate is a synthetic corticosteroid used to treat steroid-responsive eye inflammation. |
| In vivo study | Hourly local administration of the suspended drug reduced polymorphonuclear leukocyte invasion of the corneal stroma by an average of 46.8%. In the cornea, fluorometholone acetate appears to have a better efficacy than fluorometholone alcohol in reducing the number of white blood cells that invade the tissue causing the inflammatory response. Animal toxicological studies of fluorometholone, including acute intraperitoneal LD50s in rats and mice, subacute oral toxicity in dogs and rats, and subacute local ocular toxicity in rabbits, have demonstrated the safety of this drug for use in humans. |
NSC 47438 - Risk and Safety
| HS Code | 2937220000 |
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Product Name: Fluorometholone Acetate Visit Supplier Webpage Request for quotationCAS: 3801-06-7
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Product Name: Fluorometholone acetate Visit Supplier Webpage Request for quotationCAS: 3801-06-7
Tel: +86-18821248368
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View History
NSC 47438
1-Hydroxy Valdecoxib
5-METHANESULFONYL-6-NITRO-3H-BENZOXAZOL-2-ONE
1,4-Diazobicylco[3.2.2]Nonane
正癸酰基-L-高丝氨酸内酯
Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2-methoxyphenyl)methyl]-
2-十七基咪唑
3-氨基-5,6-二氯吡嗪-2-甲酸甲酯
3-(2'-螺旋金刚烷)-4-甲氧基-4-(3''-磷酰氧基)苯-1,2-二氧杂环丁烷
Permanent Red F4R
1-Hydroxy Valdecoxib
5-METHANESULFONYL-6-NITRO-3H-BENZOXAZOL-2-ONE
1,4-Diazobicylco[3.2.2]Nonane
正癸酰基-L-高丝氨酸内酯
Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2-methoxyphenyl)methyl]-
2-十七基咪唑
3-氨基-5,6-二氯吡嗪-2-甲酸甲酯
3-(2'-螺旋金刚烷)-4-甲氧基-4-(3''-磷酰氧基)苯-1,2-二氧杂环丁烷
Permanent Red F4R