N-methyl-4-nitrotoluenesulphonamide - Names and Identifiers
N-methyl-4-nitrotoluenesulphonamide - Physico-chemical Properties
Molecular Formula | C8H10N2O4S
|
Molar Mass | 230.24 |
Density | 1.404±0.06 g/cm3(Predicted) |
Melting Point | 151-153°C |
Boling Point | 417.5±47.0 °C(Predicted) |
Flash Point | 206.3°C |
Vapor Presure | 3.53E-07mmHg at 25°C |
pKa | 10.69±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.579 |
MDL | MFCD00277775 |
N-methyl-4-nitrotoluenesulphonamide - Introduction
N-methyl-4-nitrotoluenesulphonamide is an organic compound with the chemical formula C8H10N2O4S. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in alcohol, ketone and dimethylthionamide, slightly soluble in water
-Melting point: 135-136°C
-Density: 1.45g/cm³
Use:
- N-methyl-4-nitrotoluenesulphonamide is an important organic synthesis intermediate, which can be used to synthesize various organic compounds.
-In the field of medicine, it can be used as a synthetic intermediate of drugs, and is widely used in chemical evaluation and biological activity research.
Preparation Method:
-The preparation of N-methyl-4-nitrotoluenesulphonamide is usually obtained by reacting p-methyltoluenesulfonyl chloride with nitric acid. The specific steps are as follows:
-Dissolve p-methyltoluenesulfonyl chloride in anhydrous chlorinated methane, add nitric acid and slowly drop it, and react at low temperature.
-After completion of the reaction, the product is cooled and purified by crystallization to obtain the N-methyl-4-nitrotoluenesulphonamide product.
Safety Information:
- N-methyl-4-nitrotoluenesulphonamide is a chemical that needs to be stored away from heat, fire and oxidizing agents.
-During use, it is recommended to wear appropriate protective gloves, protective glasses and protective masks to ensure safe operation.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When handling and disposing of waste, follow local regulations to ensure environmental safety.
Last Update:2024-04-09 15:18:00