N-Cbz-cis-4--fluoro-L-proline - Names and Identifiers
N-Cbz-cis-4--fluoro-L-proline - Physico-chemical Properties
N-Cbz-cis-4--fluoro-L-proline - Introduction
N-Cbz-cis-4-fluoro-L-proline is an organic compound with the chemical formula C20H18FNO4, which is 4-fluoro-L-proline in cis conformation with N-Cbz (N-benzylmethyl) as the protecting group. Next to introduce:
Nature:
N-Cbz-cis-4 -- fluoro-L-proline is a white to yellowish solid. It has good solubility at room temperature, and has high solubility in some organic solvents such as dichloromethane, dimethyl sulfoxide and dimethylformamide. The compound has a melting point of 170-173°C.
Use:
N-Cbz-cis-4-fluoro-L-proline is mainly used in organic synthesis reactions and as an intermediate for the synthesis of other biologically active molecules. It can be used as a raw material in the synthesis of drugs, for example, for the synthesis of fluorine-containing proline drugs or proline analogs. In addition, N-Cbz-cis-4-fluoro-L-proline can also be used to study the properties and reactions of L-proline and related amino acids.
Preparation Method:
The preparation of N-Cbz-cis-4-fluoro-L-proline is usually carried out by chemical synthesis methods. A common method is to react N-Cbz-L-proline with an appropriate amount of fluorinating agent in an organic solvent to obtain N-Cbz-cis-4-fluoro-L-proline. The synthesis process requires a certain protection group operation, and needs to control the reaction conditions and reaction time.
Safety Information:
N-Cbz-cis-4-fluoro-L-proline generally have low safety risks when used and stored correctly, but the following matters still need to be noted:
1. When handling the compound, appropriate personal protective measures should be taken, such as wearing gloves, laboratory clothes, etc.
2. avoid direct contact with the skin, eyes, such as accidental contact, should immediately rinse with plenty of water and seek medical help.
3. During storage, avoid contact with oxidants and combustibles, keep sealed, and store in a dry and cool place.
4. Follow the laboratory safety operation procedures during use and operate according to the safety data sheet provided by the specific material.
It should be noted that the information provided above is for reference only. In specific applications, please follow the safety regulations of the laboratory and refer to the exact chemical substance safety data sheet.
Last Update:2024-04-09 20:52:54