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N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID

N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID

CAS: 129365-23-7;126937-41-5

Molecular Formula: C22H32N2O6

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N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID - Names and Identifiers

Name N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID
Synonyms 1-BENZYLOXYCARBONYL-4-PIPERIDONE
4-BOC-1-CBZ-PIPERAZINE-2-CARBOXYLIC ACID
1-Boc-4-Cbz-2-Piperazine carboxylic acid
4-Boc-1-Cbz-2-Piperazine carboxylic acid
Boc-4-Cbz-2-Piperazine carboxylic acid
4-N-BOC-1-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID
N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID
1-N-Boc-4-N-Cbz-2-Piperazinecarboxylic acid t-butyl ester
N-1-BOC-N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID T-BUTYL ESTER
(±)-1-Benzyloxycarbonyl-4-Boc-piperazine-2-carboxylic acid
PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-BENZYL ESTER 4-TERT-BUTYL ESTER
N1-Benzyloxycarbonyl-N4-tert-butoxycarbonyl-2-piperazinecarboxylic acid
4-[(benzyloxy)carbonyl]-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
1-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
(2R)-1-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylate
1-benzyloxycarbonyl-4-(2,2-dimethylpropanoyloxy)piperazine-2-carboxylic acid
(2S)-1-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylate
CAS 129365-23-7
126937-41-5
InChI InChI=1/C18H24N2O6/c1-18(2,3)16(23)26-19-9-10-20(14(11-19)15(21)22)17(24)25-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,22)

N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID - Physico-chemical Properties

Molecular FormulaC22H32N2O6
Molar Mass420.5
Density1.29g/cm3
Melting Point150-152℃
Boling Point520°C at 760 mmHg
Flash Point268.3°C
Vapor Presure1.22E-11mmHg at 25°C
Refractive Index1.575

N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID - Introduction

N-4-tert-butoxycarbonyl-N-1-benzyloxycarbonyl-2-piperazinecarboxylic acid, chemical name tert-butyl N-benzyl-N-(2-piperidinyl)carbamate. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: Usually a white crystalline solid.
-Melting point: approximately in the range of 78-81°C.
-Molecular formula: C19H28N2O3.
-Molecular weight: 332.44g/mol.

Use:
- N-4-tert-butoxycarbonyl-N-1-benzyloxycarbonyl-2-piperazinecarboxylic acid is a commonly used intermediate in organic synthesis.
-It can be used to synthesize drugs, such as antiepileptic drugs, such as the precursor of furosinic acid (Phenobarbital).
-It can also be used as a reagent in scientific research.

Preparation Method:
- N-4-tert-butoxycarbonyl-N-1-benzyloxycarbonyl-2-piperazinecarboxylic acid is usually prepared by chemical synthesis.
-A common preparation method is to react 1-benzyl-2-piperazinamine with tert-butyryl chloride (t-butyl isocyanate), and use appropriate solvents and conditions for the reaction.
-The specific steps and conditions of this synthesis method can be adjusted according to actual needs.

Safety Information:
- N-4-tert-butoxycarbonyl-N-1-benzyloxycarbonyl-2-piperazinecarboxylic acid has limited safety information, so appropriate safety measures should be taken when using and handling.
-Specific safety information should refer to the safety data sheet (SDS) of the chemical.
-In case of skin contact or inhalation, rinse immediately with water and seek medical help.
-The preparation and handling of this compound should be carried out under proper ventilation conditions and wear appropriate personal protective equipment.

Please note that the information provided here is for reference only. When using and handling chemical substances, please always follow the laboratory's operating procedures and safety instructions, and refer to the safety data sheet of the relevant chemical.
Last Update:2024-04-09 20:49:11
N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID
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