N-(4-Methoxyphenyl)-4-piperidinamine - Names and Identifiers
N-(4-Methoxyphenyl)-4-piperidinamine - Physico-chemical Properties
Molecular Formula | C12H18N2O
|
Molar Mass | 206.28 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD06740344 |
N-(4-Methoxyphenyl)-4-piperidinamine - Risk and Safety
N-(4-Methoxyphenyl)-4-piperidinamine - Introduction
N-(4-Methoxyphenyl)-4-piperidinamine(N-(4-Methoxyphenyl)-4-piperidinamine) is an organic compound. Its chemical structure contains a piperidine ring and a methoxyphenyl functional group.
The properties of the compound are as follows:
-Appearance: White solid
-Molecular formula: C14H20N2O
-Molecular weight: 232.32g/mol
-Melting point: about 100-110°C
-Soluble: Soluble in common organic solvents
N-(4-Methoxyphenyl)-4-piperidinamine has certain application value in the field of medicinal chemistry. It can be used as an intermediate in the field of medicine for the synthesis of various compounds with biological activity. At the same time, due to its ability to affect neurotransmitters, the compound can also be used as a synthetic intermediate for antidepressant drugs and sedatives.
The method for preparing N-(4-Methoxyphenyl)-4-piperidinamine is relatively simple, and a common synthetic route is as follows:
1. First, 4-methoxyphenyl boronic acid and 1-piperidinyl ethanol are reacted in the presence of an acid catalyst to prepare 4-methoxyphenyl-1-piperidinyl ethanol.
2. Then, 4-methoxyphenyl-1-piperidinyl ethanol is reacted with ammonia gas, and under the action of a reducing agent, N-(4-Methoxyphenyl)-4-piperidinamine is obtained.
Regarding safety information, N-(4-Methoxyphenyl)-4-piperidinamine has low toxicity and danger, but the following matters still need to be paid attention:
-Wear appropriate protective gloves, goggles and lab coats during operation.
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Avoid fire and high temperature during storage and handling.
Although there is no clear report of major hazards to human health and the environment, it should be handled with caution before use and follow relevant laboratory safety regulations and operating procedures.
Last Update:2024-04-09 21:01:54