N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide) - Names and Identifiers
Name | N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide)
|
Synonyms | BAC NSC 328582 BIS-ACRYLYLCYSTAMINE BISACRYLOYLCYSTAMINE N,N'-Bisacrylylcystamine N,N'-DIACRYLOYLCYSTAMINE CYSTAMINE-N,N'-BISACRYLAMIDE N N'-CYSTAMINE-BIS-ACRYLAMIDE 2,2'-BISACRYLAMIDOETHYL DISULFIDE 2,2'-(BISACRYLAMINO)DIETHYL DISULFIDE N,N'-(Dithiodi-2,1-ethanediyl)bis(acrylamide) N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide) 2-Propenamide, N,N'-(dithiodi-2,1-ethanediyl)bis- N,N'-(disulfanediyldiethane-2,1-diyl)bisprop-2-enamide
|
CAS | 60984-57-8
|
EINECS | 262-546-8 |
InChI | InChI=1/C10H16N2O2S2/c1-3-9(13)11-5-7-15-16-8-6-12-10(14)4-2/h3-4H,1-2,5-8H2,(H,11,13)(H,12,14) |
N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide) - Physico-chemical Properties
Molecular Formula | C10H16N2O2S2
|
Molar Mass | 260.38 |
Density | 1.164±0.06 g/cm3(Predicted) |
Melting Point | 121-125°C |
Boling Point | 538.0±50.0 °C(Predicted) |
Flash Point | 279.2°C |
Water Solubility | Soluble in acetic acid. Slightly soluble in water. |
Solubility | acetic acid: 50mg/mL |
Vapor Presure | 1.21E-11mmHg at 25°C |
Appearance | Powder, Packaged under argon |
pKa | 13.98±0.46(Predicted) |
Storage Condition | -20°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Refractive Index | 1.548 |
MDL | MFCD00036225 |
N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide) - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 8 |
N,N'-(dithiodi-2,1-ethanediyl)bis(acrylamide) - Introduction
N,N'-Bis (acrylamide) cystamine is an organic compound with the chemical formula C10H14N2O2S2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Usually colorless or yellowish solid.
-Solubility: Soluble in water and organic solvents such as dimethyl sulfoxide and dimethylformamide.
-Melting point: about 100-105 degrees Celsius.
-Density: about 1.18 g/ml.
-Stability: relatively stable under conventional experimental conditions.
Use:
N,N'-Bis (acrylamide) cystamine has many applications in the chemical and biological fields:
-As a crosslinking agent: Due to its bisacrylamide structure, it can form crosslinking between polymers and biological macromolecules, which is used to prepare hydrogels, hydrogel microspheres, etc.
-In biomedical research: It can be used to modify biological macromolecules, such as proteins, peptides and nucleic acids, for biological activity research or the construction of drug delivery systems.
-In organic synthesis reactions: as a catalyst or participate in a variety of chemical reactions.
Preparation Method:
N,N'-Bis (acrylamide) cystamine is generally prepared by the following steps:
1.2-mercaptoacetaldehyde is reacted with acrylamide to obtain 2-mercaptovinylamine.
2. Reaction of 2-mercaptovinylamine with diacrylamide under alkaline conditions to form N,N'-bis (acrylamide) cystamine.
Safety Information:
- N,N'-Bis (acrylamide) cystamine is not significantly toxic under routine laboratory conditions, but any chemical should be handled with caution to avoid contact with skin, eyes and inhalation.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coatings when using.
-Operate under airtight ventilation conditions to avoid inhaling dust or vapors.
-Avoid contact with oxidants, strong acids, strong alkalis and other substances during storage to avoid fire sources.
Last Update:2024-04-09 21:04:16