N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine - Names and Identifiers
Name | N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine
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Synonyms | N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine N2,O5'-diacetyl-O2',O3'-isopropylidene-guanosine 2N, 5'-O-Diacetyl-2',3'-O-Isopropylide ne Guanosi 2N, 5'-O-Diacetyl-2',3'-O-Isopropylide ne Guanosine N-Acetyl-2',3'-O-isopropylidene-guanosine 5'-Acetate Guanosine, N-acetyl-2',3'-O-(1-methylethylidene)-, 5'-acetate ((3AR,4R,6R,6aR)-6-(2-acetamido-6-oxo-1H-purin-9(6H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl acetate
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CAS | 106743-56-0
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N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine - Physico-chemical Properties
Molecular Formula | C17H21N5O7
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Molar Mass | 407.38 |
Density | 1.68 |
Melting Point | 124-125 ºC |
pKa | 9.07±0.20(Predicted) |
N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine - Introduction
N,5 '-O-diacetyl-2',3 '-O-isopropoxyguanosine is an organic compound with the chemical formula C18H25N5O8. The following is information about its nature, use, formulation and safety:
Nature:
-Appearance: White solid
-melting point: 197-204 ℃
-Solubility: Slightly soluble in water and alcohol solvents, insoluble in non-polar solvents
Use:
N,5 '-O-diacetyl-2',3 '-O-isopropylidene guanosine is a commonly used nucleotide modification used in biochemical and molecular biology research. It can be used as a substrate for nucleic acid synthesis, for modifying the ends of DNA and RNA strands, and as a chemical modifier for exploring the structure and function of nucleic acids.
Preparation Method:
N,5 '-O-diacetyl -2',3 '-O-isopropylidene guanosine preparation method is more complex, generally need to be achieved by chemical synthesis. Specific synthetic routes and steps may involve multiple organic synthesis reactions, such as esterification, substitution reactions, acid-base treatment, etc. Due to the high demand for synthesis, it generally needs to be prepared in the laboratory or large-scale chemical production.
Safety Information:
Few specific safety information and toxicity data on N,5 '-O-diacetyl-2',3 '-O-isopropylidene guanosine have been published. In general, because it is a chemically synthesized organic compound, appropriate laboratory handling and storage measures should be taken to avoid exposure and ingestion. During use, wear appropriate protective gloves and eye protection equipment, and ensure that the laboratory has good ventilation conditions.
In addition, we should strictly abide by the relevant laboratory safety operation specifications, such as laboratory management system, waste disposal, etc., to ensure the safety of personnel and the protection of the environment. For detailed safety information and toxicity data, it may be necessary to refer to more specific chemical literature or contact the relevant chemical supplier.
Last Update:2024-04-10 22:29:15