N'-Cbz-L-鸟氨酸
N-delta-cbz-L-ornithine
CAS: 3304-51-6
Molecular Formula: C13H18N2O4
N'-Cbz-L-鸟氨酸 - Names and Identifiers
| Name | N-delta-cbz-L-ornithine |
| Synonyms | Orn(Z) H-ORN(Z)-OH H-Orn(Z)-OH H-ORN(CBZ)-OH L-Orn(Cbz)-OH L-ORNITHINE(CBZ) N5-Cbz-L-ornithine N'-Cbz-L-Ornithine N'-Cbz-L-ornithine N-d-CBZ-L-Ornithine N-delta-cbz-L-ornithine N5-benzyloxycarbonyl-L-ornithine N-5-BENZYLOXYCARBONYL-L-ORNITHINE N~5~-[(benzyloxy)carbonyl]ornithine N-?-CBZ-L-Ornithine N-?-Carbobenzyloxy-L-ornithine (2S)-2-ammonio-5-{[(benzyloxy)carbonyl]amino}pentanoate (2S)-2-amino-5-{[(benzyloxy)carbonyl]amino}pentanoic acid |
| CAS | 3304-51-6 |
| EINECS | 221-980-8 |
| InChI | InChI=1/C13H18N2O4/c14-11(12(16)17)7-4-8-15-13(18)19-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9,14H2,(H,15,18)(H,16,17)/t11-/m0/s1 |
N'-Cbz-L-鸟氨酸 - Physico-chemical Properties
| Molecular Formula | C13H18N2O4 |
| Molar Mass | 266.29 |
| Density | 1.234±0.06 g/cm3(Predicted) |
| Melting Point | 248-252℃ |
| Boling Point | 492.2±45.0 °C(Predicted) |
| Flash Point | 251.4°C |
| Solubility | Acidic Alcohol (Sparingly), Aqueous Acid (Slightly) |
| Vapor Presure | 1.67E-10mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | 2.51±0.24(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.556 |
| MDL | MFCD00037220 |
N'-Cbz-L-鸟氨酸 - Risk and Safety
| WGK Germany | 3 |
N'-Cbz-L-鸟氨酸 - Reference Information
| Application | N'-Cbz-L-ornithine is an amino acid derivative that can be used as an intermediate in organic synthesis and a pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. |
| preparation | to L-ornithine hydrochloride (5.0g,29.7mmol) in aqueous sodium hydroxide solution (50ml, 0.5M) to this solution was added a solution of copper sulfate (17.8g, mmol) in water (ml), and the mixture was stirred at room temperature for 4 hours. The mixture was then cooled to 0 °c before sodium bicarbonate (5.0g,59.4mmol) and benzyl chloroformate (5.7mL,40.1mmol) were added. The pH was then adjusted to pH 9 by careful addition of aqueous sodium hydroxide (1.0M) and the mixture was stirred at room temperature for 4 hours. The resulting solid was collected by filtration, washed with water, then ether, dissolved in aqueous EDTA (0.5 ml, M) and stirred vigorously at room temperature for 14 hours. The solid was again collected by filtration and washed with water to give crude solid N'-Cbz-L-ornithine, which was used without further purification. |
Last Update：2024-04-09 15:16:40
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View History
N'-Cbz-L-鸟氨酸
SILVER SUCCINIMIDE)
扎那米韦(抗流感药)
右旋-3-溴樟脑-10-磺酸一水合物
N-(苯并[d][1,3]二氧戊环-5-基甲基)环戊胺盐酸盐
2,5-二氨基噻唑并[4,5-d]嘧啶-7(4H)-酮
2-氨基-4-甲氧基-1-硝基苯3-氨基-4-硝基苯胺
[2H5]-Methyl Desoxycholate
氨基-4-酮-2-(四氮唑-5-基)-4H-1-苯并吡喃盐酸盐
2-氟-6-氯苯甲酸酰胺
SILVER SUCCINIMIDE)
扎那米韦(抗流感药)
右旋-3-溴樟脑-10-磺酸一水合物
N-(苯并[d][1,3]二氧戊环-5-基甲基)环戊胺盐酸盐
2,5-二氨基噻唑并[4,5-d]嘧啶-7(4H)-酮
2-氨基-4-甲氧基-1-硝基苯3-氨基-4-硝基苯胺
[2H5]-Methyl Desoxycholate
氨基-4-酮-2-(四氮唑-5-基)-4H-1-苯并吡喃盐酸盐
2-氟-6-氯苯甲酸酰胺