Metaproterenol Sulfate
Metaproterenol Sulfate
CAS: 5874-97-5
Molecular Formula: C22H36N2O10S
Metaproterenol Sulfate - Names and Identifiers
Metaproterenol Sulfate - Physico-chemical Properties
| Molecular Formula | C22H36N2O10S |
| Molar Mass | 520.59 |
| Melting Point | 202-203° |
| Solubility | Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
| Appearance | neat |
| Color | White to Off-White |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
| In vivo study | Treatment of Zucker diabetic fatty rats with Metaproterenol for 12 weeks attenuates monocyte activation as well as pro-inflammatory and pro-fibrotic responses in the kidneys and heart. Thus, Metaproterenol might has protective effects against diabetic renal and cardiovascular complications. |
Metaproterenol Sulfate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20 - Harmful by inhalation |
| Safety Description | 36 - Wear suitable protective clothing. |
| WGK Germany | 2 |
| RTECS | DO2275000 |
| HS Code | 2922504500 |
| Toxicity | LD50 in rats (mg/kg): 42 orally (Goldenthal) |
Metaproterenol Sulfate - Reference Information
| biological activity | , it is a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity.|
| Target | IC50: 68 nM |
| Cell Line: | THP-1 cells and bone marrow macrophages THP-1 cells and bone marrow macrophages |
| Concentration: | 10 μM 10 μM |
| Incubation Time: | 74 hours 74 hours |
| Result: | Enhanced β-arrestin2 and its interaction with IκBα. Led to downregulation of NF-κB. |
Last Update：2024-04-09 21:01:54
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Product Name: Metaproterenol sulfate Visit Supplier Webpage Request for quotationCAS: 5874-97-5
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View History
Metaproterenol Sulfate
1361855-93-7
31698-96-1
5-Thiazolemethanamine, α,4-dimethyl-2-(1-piperidinyl)-
(3R)-3α-Methoxy-4α-(methylthio)-2-piperidinethione
6H-Purin-6-one, 9-[3-(4-amino-2-oxo-1(2H)-pyrimidinyl)propyl]-2-(dimethylamino)-1,9-dihydro-
GLUCAGON 37
β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester
50767-78-7
1432681-26-9
1361855-93-7
31698-96-1
5-Thiazolemethanamine, α,4-dimethyl-2-(1-piperidinyl)-
(3R)-3α-Methoxy-4α-(methylthio)-2-piperidinethione
6H-Purin-6-one, 9-[3-(4-amino-2-oxo-1(2H)-pyrimidinyl)propyl]-2-(dimethylamino)-1,9-dihydro-
GLUCAGON 37
β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester
50767-78-7
1432681-26-9