MPPF(2 '-[18F]Fluoro-3'-(2-methoxyphenyl)propylidene]thiosemicarbazone) is a radioactive fluorescent imaging agent commonly used in the diagnosis and research of tumors.
Properties of MPPF:
- MPPF is a radioactive compound whose molecular structure contains the 18F radioactive isotope.
- MPPF is a solid with a white to light yellow color.
-It has high chemical stability and can stably perform fluorescence imaging in the body.
Purpose of MPPF:
- MPPF is mainly used to help diagnose and evaluate the activity and distribution of tumor tissue through positron emission tomography (PET) technology.
-It can be used in conjunction with the PET scanner commonly used in clinic to provide high-resolution images.
- MPPF can also be used to study the biological characteristics of tumors, drug delivery and treatment response.
preparation method of MPPF:
- MPPF synthesis method is more complex, generally need to be completed by multi-step reaction.
-The preparation method includes the steps of fluorine -18 labeling of the precursor compound, esterification reaction and thizone reaction.
safety information of MPPF:
-because MPPF is a radioactive material, the use and operation of the need to strictly follow the principles of radiation safety and related procedures.
-Operators need to receive relevant radiation safety training and wear necessary personal protective equipment, such as gloves, goggles and lab clothes.
-Experiments should be conducted in a well-equipped Radiation Laboratory, complying with the requirements for storage, handling and waste disposal of radioactive materials.
-The distribution and metabolism of MPPF in the body requires monitoring and evaluation by clinical professionals to ensure safe use conditions.