METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE
METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE
CAS: 79481-83-7
Molecular Formula: C15H21Cl2NO2
METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE - Names and Identifiers
METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE - Physico-chemical Properties
| Molecular Formula | C15H21Cl2NO2 |
| Molar Mass | 318.23874 |
METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE - References
| use | tumor-based intermediate. |
| Production method | Use acetanilide and succinic anhydride to form β-(p-acetaminobenzoyl) propionic acid with the participation of anhydrous aluminum trichloride, and then react with hydrazine hydrate and potassium hydroxide (hydrolysis and reduction), and acidify with acetic acid to obtain 4-(p-aminophenyl) butyric acid, which is esterified with methanol under the action of hydrogen chloride, then neutralize, and then use ethylene oxide hydroxyethyl to obtain 4-{[bis (β-hydroxyethyl) amino] phenyl} methyl butyrate, and then use phosphorus oxychloride to produce the product. |
Last Update：2024-04-10 22:29:15
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METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE
1H-Pyrazole, compd. with benzene (1:1)
2-氰基-N-(4-氨基磺酰基苄基)乙酰胺
(1-(叔丁基二甲基甲硅烷基)-1H-吲哚-5-基)硼酸
2-胺基-5-苯基噻吩-3-甲酸甲酯
(2S,3S)-2-氨基-3-羟基丁酸甲酯盐酸盐
6-溴-3-[[(2-甲氧基苯基)氨基]羰基]-2-萘基 BETA-D-吡喃葡糖苷酸
3-氟-4-(三氟甲基)苄溴
2-溴-4-甲基苯并[D]噻唑-6-羧酸甲酯
Boc-D-2,4,5-三氟苯基丙氨酸
1H-Pyrazole, compd. with benzene (1:1)
2-氰基-N-(4-氨基磺酰基苄基)乙酰胺
(1-(叔丁基二甲基甲硅烷基)-1H-吲哚-5-基)硼酸
2-胺基-5-苯基噻吩-3-甲酸甲酯
(2S,3S)-2-氨基-3-羟基丁酸甲酯盐酸盐
6-溴-3-[[(2-甲氧基苯基)氨基]羰基]-2-萘基 BETA-D-吡喃葡糖苷酸
3-氟-4-(三氟甲基)苄溴
2-溴-4-甲基苯并[D]噻唑-6-羧酸甲酯
Boc-D-2,4,5-三氟苯基丙氨酸