| Production method | Use acetanilide and succinic anhydride to form β-(p-acetaminobenzoyl) propionic acid with the participation of anhydrous aluminum trichloride, and then react with hydrazine hydrate and potassium hydroxide (hydrolysis and reduction), and acidify with acetic acid to obtain 4-(p-aminophenyl) butyric acid, which is esterified with methanol under the action of hydrogen chloride, then neutralize, and then use ethylene oxide hydroxyethyl to obtain 4-{[bis (β-hydroxyethyl) amino] phenyl} methyl butyrate, and then use phosphorus oxychloride to produce the product. |
