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Licorin hydrochloride

Lycorine hydrochloride

CAS: 2188-68-3

Molecular Formula: C16H17NO4

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Licorin hydrochloride - Names and Identifiers

Name Lycorine hydrochloride
Synonyms LYCORIN
LYCORINE
Lycorine HCl
(-)-LYCORINE
NARCISSIN(P)
Hydrochloric Lycorine
Licorin hydrochloride
Lycorine hydrochloride
Galanthidine hydrochloride
Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)-
CAS 2188-68-3
InChI InChI=1/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

Licorin hydrochloride - Physico-chemical Properties

Molecular FormulaC16H17NO4
Molar Mass287.31
Melting Point206 °C
Boling Point477.4°C at 760 mmHg
Specific Rotation(α)+43°
Flash Point242.5°C
Solubility DMSO : 25 mg/mL (77.22 mM; Need ultrasonic)
Vapor Presure6.37E-10mmHg at 25°C
AppearanceWhite powder
ColorWhite to off-white
Storage ConditionKeep in dark place,Inert atmosphere,2-8°C
StabilityStable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month.
SensitiveSensitive to light
MDLMFCD00243111
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Lycoris radiata bulbs.

Licorin hydrochloride - Risk and Safety

Hazard SymbolsT - Toxic
Toxic
Risk Codes25 - Toxic if swallowed
Safety Description45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 2811 6.1/PG 3
WGK Germany3

Licorin hydrochloride - Reference

Reference
Show more
1. Niu Wei and Pan Dongming. Study on Extraction Methods of Narcissus Alkaloids from China [J]. Anhui Agricultural Sciences 2012(19):10018-10019.
2. Peng Cong, Xu Jia, Wu Chunlian. Effects of Lycorine Hydrochloride on Eca-109 Proliferation and Apoptosis of Human Esophageal Cancer Cells [J]. Journal of Xihua Normal University (Natural Science Edition), 2015(36):7-11.
3. [IF = 2.044] Xu Chen et al."Ionic-Liquid-Based Infrared-Assisted Extraction (IL-IRAE) Coupled with HPLC-MS: a Green and Convenient Tool for Determination of TCMs." Chromatographia. 2017 Feb;80(2):335-340

Licorin hydrochloride - Nature

Open Data Verified Data

crystals of colorless prisms. Melting point 275~280 °c (decomposition). Insoluble in water, slightly soluble in ethanol, the stems and branches of ephedrine cut into 2 ~ 4cm long, plus chloroform and petroleum ether, soluble in acidic aqueous solution. Its commercial form is usually its hydrochloride, the crystals of which are long needle-like crystals with a melting point of 217 ° C. (decomposition).

Last Update:2024-01-02 23:10:35

Licorin hydrochloride - Preparation Method

Open Data Verified Data

It is usually extracted from Lycoris radiata. Take Lycoris sativa L. Bulb powder, extract with ethanol reflux for 6h, cool, filter, extract repeatedly for 3 times, combine the filtrate, concentrate to dryness; Dissolve the concentrate with 2% hydrochloric acid, filter, the filtrate was washed with chloroform; The acid water washed with chloroform was basified with Na2 C03, and then chloroform was added to precipitate lycorine solid in the middle of the chloroform alkaline water layer. After filtration, it was dissolved and concentrated with 2% HC1, crystal available lycorine hydrochloride. Pseudoephedrine.

Last Update:2022-01-01 11:15:16

Licorin hydrochloride - Use

Open Data Verified Data

small doses have expectorant effect, large doses of oxalic acid to add 8~10 times the water and vomiting effect, but also have spasmolytic effect.

Last Update:2022-01-01 11:15:16
Licorin hydrochloride
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MedChemExpress (MCE)
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Product Name: Lycorine hydrochloride (Standard) Visit Supplier Webpage Request for quotation
CAS: 2188-68-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
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Mobile: 609-228-6898
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CAS: 2188-68-3
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CAS: 2188-68-3
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CAS: 2188-68-3
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: Lycorine hydrochloride Visit Supplier Webpage Request for quotation
CAS: 2188-68-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Lycorine chloride Visit Supplier Webpage Request for quotation
CAS: 2188-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Licorin hydrochloride
(S)-7-溴-1,2,3,4-四氢-萘-1-基胺
牛磺脱氧胆酸钠盐
7-Methoxy-1-methyl-2-tetralone
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