Name | L-Isoleucine |
Synonyms | Ile L-Ile L-Ile-OH H-Ile-OH Isoleucine Isoleucina Isoleucinum iso-leucine L-Isoieucine L-ISOLEUSINE L-Isoleucine Isoleucine, L- L-(+)-Isoleucine Isoleucine (USP) (2S,3S)-(+)-Isoleucine 2-Amino-3-methylvaleric acid L-(+)-Isoleucine, Animal-Free L-2-Amino-3-methylvaleric Acid (2S,3S)-2-Amino-3-methylpentansαure 6-Amino-5-ethylamino-1-methyluracil (2S)-2-Amino-3-methylpentanoic acid (2S,3S)-a-Amino-b-methylvaleric acid (2S,3S)-2-amino-3-methyl-Pentanoic acid (2S,3S)-a-Amino-b-methyl-n-valeric acid (2s,3s)-alpha-amino-beta-merthylvalericacid (2s,3s)-alpha-amino-beta-methyl-n-valericacid |
CAS | 73-32-5 131598-62-4 |
EINECS | 200-798-2 |
InChI | InChI=1/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1 |
InChIKey | AGPKZVBTJJNPAG-WHFBIAKZSA-N |
Molecular Formula | C6H13NO2 |
Molar Mass | 131.17 |
Density | 1.2930 (estimate) |
Melting Point | 288 °C (dec.) (lit.) |
Boling Point | 225.8±23.0 °C(Predicted) |
Specific Rotation(α) | 41 º (c=4, 6N HCl) |
Flash Point | 168-170°C |
JECFA Number | 2118 |
Water Solubility | 41.2 g/L (50 ºC) |
Solubility | The solubility in water is 4.12%, which is extremely difficult to dissolve in ethanol and ether. |
Appearance | White crystal or crystalline powder |
Color | White to Off-white |
Maximum wavelength(λmax) | λ: 260 nm Amax: 0.07λ: 280 nm Amax: 0.05 |
Merck | 14,5179 |
BRN | 1721792 |
pKa | 2.32, 9.76(at 25℃) |
PH | 5.5-6.5 (40g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Refractive Index | 40.5 ° (C=4, 6mol/L |
MDL | MFCD00064222 |
Physical and Chemical Properties | Melting point 168-170°C sublimation point 168-170°C specific optical rotation 41 ° (c = 4, 6N HCl) water-soluble 41.2g/L (50°C) |
Use | Used as amino acid injection, compound amino acid infusion, food additives |
Hazard Symbols | Xn - Harmful |
Risk Codes | 40 - Limited evidence of a carcinogenic effect |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S22 - Do not breathe dust. |
WGK Germany | 3 |
RTECS | NR4705000 |
TSCA | Yes |
HS Code | 29224995 |
Toxicity | LD50 intraperitoneal in rat: 6822mg/kg |
Raw Materials | Dextrose Anhydrate Ammonia |
This product is white crystal or crystalline powder; Odorless, slightly bitter taste. Melting point 284 C (decomposition),168~170 C sublimation. Slightly soluble in water (4.12%,25 °c), practically insoluble in ethanol and ether. It is an essential amino acid, is one of the three branched chain amino acids, oxidative decomposition can release more energy, per mole of isoleucine can produce 43mol ATP. The metabolic site is mainly in the muscle, which is a sugar and ketogenic amino acid. The metabolic process not only releases acetyl CoA, but also generates succinic acid. It has the effect of promoting insulin secretion. Lack of L-isoleucine can cause skeletal muscle disorders. It has a competitive inhibitory effect with the other two branched chain amino acids.
fermentation method
amino acid drugs. For nutritional supplements, mixed with other carbohydrates, inorganic salts and vitamins for injection. Compatibility with other amino acids for amino acid infusion and preparation.