HLCL 61 HYDROCHLORIDE
HLCL-61 (hydrochloride)
CAS: 1158279-20-9
Molecular Formula: C23H25ClN2O
HLCL 61 HYDROCHLORIDE - Names and Identifiers
HLCL 61 HYDROCHLORIDE - Physico-chemical Properties
| Molecular Formula | C23H25ClN2O |
| Molar Mass | 380.92 |
| Solubility | DMSO: ≥ 30 mg/mL |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
HLCL 61 HYDROCHLORIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.625 ml | 13.126 ml | 26.253 ml |
| 5 mM | 0.525 ml | 2.625 ml | 5.251 ml |
| 10 mM | 0.263 ml | 1.313 ml | 2.625 ml |
| 5 mM | 0.053 ml | 0.263 ml | 0.525 ml |
Last Update：2024-01-02 23:10:35
HLCL 61 HYDROCHLORIDE - Reference Information
| biological activity | HLCL-61 hydroxyapatite is the first small molecule protein arginine methyltransferase 5 (PRMT5) inhibitor. |
| Target | Protein arginine methyltransfer 5 |
| Cell Line: | MV4-11 cells, THP-1 cells, FLT3-WT blast (primary blasts from patients), FLT3-ITD blast (primary blasts from patients) |
| Concentration: | 1, 5, 10, 25, 50, 100 μM |
| Incubation Time: | 24, 48, 72 hours |
| Result: | Dose-dependent reduction in cell viability with IC 50 s of 14.12, 16.74, 6.3, 8.72 μM for MV4-11 cells, THP-1 cells, FLT3-WT blast, and FLT3-ITD blast, respectively. |
Last Update：2024-04-09 19:05:17
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Spot supply
Product Name: HLCL-61 Visit Supplier Webpage Request for quotationCAS: 1158279-20-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: HLCL-61 (hydrochloride) Visit Supplier Webpage Request for quotationCAS: 1158279-20-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: HLCL61 Visit Supplier Webpage Request for quotationCAS: 1158279-20-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: HLCL-61 (hydrochloride) Visit Supplier Webpage Request for quotationCAS: 1158279-20-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
HLCL 61 HYDROCHLORIDE
1374657-02-9
9002-01-1
化合物 AMINOPEPTIDASE-IN-1
2-Furancarboxylic acid, 5-[(2,4-difluorophenoxy)methyl]-
1374657-02-9
9002-01-1
化合物 AMINOPEPTIDASE-IN-1
2-Furancarboxylic acid, 5-[(2,4-difluorophenoxy)methyl]-