Fmoc-L-2-(2-Thienyl)-glycine is an organic compound with the following properties:
1. appearance: the common form is white powder or crystalline solid.
2. solubility: soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane and ether, insoluble in water.
3. chemical structure: it is composed of L-2-(2-thienyl) glycine protected by Fmoc, where Fmoc is a protecting group to prevent the amino group from being attacked during the reaction.
4. storage: need to store in a cool and dry place, avoid direct sunlight.
The main uses of Fmoc-L-2-(2-Thienyl)-glycine are as follows:
1. Chemical synthesis: It is often used in the synthesis of polypeptides and proteins, especially in solid phase synthesis, as amino acid residues are introduced into the peptide chain for customized synthesis of peptide chains with specific functions.
2. Research: Due to the existence of 2-thienyl group, it has important application value in the fields of drug research and development, fluorescent probes and photoelectric materials.
The method for preparing Fmoc-L-2-(2-Thienyl)-glycine is as follows:
1. First, synthesize 2-thienylethanol, and then convert it into glycine through a chemical reaction.
2. Next, the synthesized 2-thienylglycine was Fmoc-protected to give the final product Fmoc-L-2-(2-Thienyl)-glycine.
Regarding safety information, Fmoc-L-2-(2-Thienyl)-glycine are generally considered safe under normal conditions of use. However, as a chemical, it can be irritating to the skin, eyes and respiratory tract. During the operation, personal protective measures are required, such as wearing gloves, glasses and masks. If you accidentally come into contact with skin or eyes, you should immediately rinse with plenty of water and seek medical attention in time. During use, attention should be paid to correct operation and storage methods to avoid unsafe reactions with other chemicals.