Name | Fertirelin |
Synonyms | FERTIRELIN Fertirelin [DES-GLY10] LH-RH, ETHYL AMIDE GLP-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-NHET PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-NHET PGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-NHET PYROGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO NHCH2CH3 (DES-GLY10,PRO-NHET9)-GONADOTROPIN-RELEASING HORMONE [DES-GLY10] LUTEINIZING HORMONE-RELEASING HORMONE, ETHYL AMIDE 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide L-prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl- 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide |
CAS | 38234-21-8 |
EINECS | 636-807-5 |
InChI | InChI=1/C55H76N16O12/c1-4-59-53(82)44-12-8-20-71(44)54(83)38(11-7-19-60-55(56)57)66-49(78)39(21-30(2)3)65-46(75)27-62-47(76)40(22-31-13-15-34(73)16-14-31)67-52(81)43(28-72)70-50(79)41(23-32-25-61-36-10-6-5-9-35(32)36)68-51(80)42(24-33-26-58-29-63-33)69-48(77)37-17-18-45(74)64-37/h5-6,9-10,13-16,25-26,29-30,37-44,61,72-73H,4,7-8,11-12,17-24,27-28H2,1-3H3,(H,58,63)(H,59,82)(H,62,76)(H,64,74)(H,65,75)(H,66,78)(H,67,81)(H,68,80)(H,69,77)(H,70,79)(H4,56,57,60)/t37-,38-,39-,40-,41-,42-,43-,44-/m0/s1 |
Molecular Formula | C55H76N16O12 |
Molar Mass | 1153.29 |
Density | 1.49±0.1 g/cm3(Predicted) |
Melting Point | >159°C (dec.) |
Solubility | DMSO (Slightly), Water (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 9.82±0.15(Predicted) |
Storage Condition | -15°C |
Refractive Index | 1.698 |
In vivo study | Fertirelin, an analog of GnRH 2.5 to 10 times more potent than native GnRH , has become the treatment of choice for reversing follicular cysts. Administration of high doses of Fertirelin is found to reduce superovulatory responses. |
Hazard Symbols | T - Toxic |
Risk Codes | 60 - May impair fertility |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |