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FLUOROMETHOLONE ACETATE (200 MG)

Fluorometholone Acetate

CAS: 3801-06-7

Molecular Formula: C24H31FO5

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FLUOROMETHOLONE ACETATE (200 MG) - Names and Identifiers

Name Fluorometholone Acetate
Synonyms eflone
Nolpitantium
FLUROMETHOLONE ACETATE
fluorometholone acetate
Fluorometholone Acetate
FLUOROMETHOLONE ACETATE (200 MG)
9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate
9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
CAS 3801-06-7
EINECS 223-270-3

FLUOROMETHOLONE ACETATE (200 MG) - Physico-chemical Properties

Molecular FormulaC24H31FO5
Molar Mass418.5
Density1.24±0.1 g/cm3(Predicted)
Melting Point230-232°
Boling Point532.1±50.0 °C(Predicted)
Specific Rotation(α)D +28° (chloroform)
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
AppearanceSolid
ColorOff-White to Light Yellow
pKa13.01±0.70(Predicted)
Storage Condition-20°C Freezer
In vitro studyFluorometholone Acetate is a synthetic corticosteroid used to treat steroid-responsive eye inflammation.
In vivo studyHourly local administration of the suspended drug reduced polymorphonuclear leukocyte invasion of the corneal stroma by an average of 46.8%. In the cornea, fluorometholone acetate appears to have a better efficacy than fluorometholone alcohol in reducing the number of white blood cells that invade the tissue causing the inflammatory response. Animal toxicological studies of fluorometholone, including acute intraperitoneal LD50s in rats and mice, subacute oral toxicity in dogs and rats, and subacute local ocular toxicity in rabbits, have demonstrated the safety of this drug for use in humans.

FLUOROMETHOLONE ACETATE (200 MG) - Risk and Safety

HS Code2937220000
FLUOROMETHOLONE ACETATE (200 MG)
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FLUOROMETHOLONE ACETATE (200 MG)
LDN-192960 3-(2,7-diMethoxyacridin-9-ylthio)propan-1-aMine
3-(2,7-二甲氧基吖啶-9-硫基)丙烷-1-氨
Naphtho[2,1-b]furan-2-carboxamide, N-[3-(4-morpholinyl)propyl]-
Acetamide,N-(2-chloro-6-methylphenyl)-2-[(2-furanylmethyl)amino]-, hydrochloride (1:1)
埃索美拉唑杂质19
4-二甲氨基苯并苯基酮
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