|Name||Ethanone, 2-chloro-1-(1-chlorocyclopropyl)- (9CI)|
2-chloro-1-(1-chlorocyclopropyl) ethyl ketone
|Boling Point||202.0±20.0 °C(Predicted)|
|Physical and Chemical Properties||Storage conditions Inert atmosphere,2-8°C|
|Use||Prothiazole is a new broad-spectrum triazolthione fungicide, which is mainly used to prevent and control diseases of crops such as cereals, wheat and beans. Its biological and ecological toxicity is good, low toxicity, no teratogenicity, mutant, non-toxic to embryos, and safe to human body and environment.|
take 118.5g of 1-(1-chlorocyclopropyl) ethanone, 237mL of dichloromethane and 9.6g of methanol in a 500mL reaction kettle, cool to 0 ℃, start to pass chlorine gas to the system, keep the reaction temperature less than 5 ℃, after passing chlorine gas for 3 hours, stop passing chlorine gas, and continue to keep the temperature for 30min. After the reaction, the chlorine and hydrogen chloride remaining in the negative pressure pumping system at 0 ℃ for 1h, and then the solvent was removed by vacuum distillation at 25 ℃/-0.1Mpa to obtain light yellow liquid 2-chloro-1-(1-chlorocyclopropyl) ethanone with 92.5% yield and 93.8% content.
2-chloro-1-(1-chloropropyl) ethanone is an important chemical intermediate and one of the important intermediates for the synthesis of propylthiazole.